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Background: Coronavirus disease 2019 (COVID-19) has infected more than 4 million people within 4 months. There is an urgent need to properly identify high-risk cases that are more likely to deteriorate even if they present mild diseases
The activites of lactic dehydrogenase (LDH), glutamicoxalactic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) are investigated within variable periods following tenotomy of m. gastrocnemius in the rat. A gradual fall of total activities is established, mostly significant for LDH, and
Membrane-mediated excessive intracellular calcium accumulation (EICA) is a fundamental pathogenetic event associated with chronic muscle degeneration in patients with Duchenne muscular dystrophy (DMD), and in animals with hereditary muscular dystrophy (HMD). Because of potential Ca(2+)-channel
Two groups of five two-year-old Hereford steers were infected with two virulent strains of B. bovis. The plasma concentrations of creatine kinase (CK), lactate dehydrogenase (LDH), and creatinine rose early in infection and showed highly significant increases terminally. Extensive skeletal muscle
The causes of human amyotrophic lateral sclerosis (ALS) and the spinal muscular atrophies (SMA) are, almost without exception, unknown. This ignorance has stimulated the search for animal models to obtain insight into the etiology, pathogenesis and biochemical mechanisms underlying the human
The neurotransmitter glutamate is neurotoxic when it is accumulated in a massive amount in the extracellular fluid. Excessive release of glutamate has been shown to be a major cause of neuronal degeneration after central nervous system injury. Under normal conditions, accumulation of synaptically
Histological and histochemical study was carried out to investigate disuse atrophy on skeletal muscle in adult albino rabbits. Untreated anterior tibial muscle and gastrocnemius muscle were studied. Three fiber types were recognized with myosin ATPase reaction, viz. type I, IIA and IIB fibers under