8 rezultatet
The clinical and psychometric evaluation of a drug to be used against the intellectual deterioration associated with cerebral aging is of obvious interest when carried out on ambulatory subjects, since the symptoms likely to be reduced are found in elderly people usually living at home. Thirty-six
Severe acute hypoglycaemia with isoelectric electroencephalogram induces a major deterioration of the energy state and amino acid contents of the brain. During post-hypoglycaemia recovery of adult animals, brain glucose concentrations return to normal values, whereas glycogen turnover remains low as
Severe hypoglycemia with isoelectric EEG induced extensive deterioration of the energy state and gross alteration of amino acid contents on the rat cerebral and cerebellar cortex. During recovery, tissue glucose concentration returned to normal, while both lactate and pyruvate concentrations
Computerized quantification of electroencephalograms enables pharmacological compounds designed to counteract pathological cerebral aging to be evaluated. The results obtained by this method when substances which sedate or stimulate the central nervous system are used suggest the existence of a
Almitrine bismesylate is thought to cause sensory peripheral neuropathy. Forty-six patients are reported who received almitrine bismesylate alone for chronic respiratory failure or in combination with raubasine for various cerebrovascular diseases. Polyneuropathy appeared between 9 and 25 months
Previously reported cases of peripheral neuropathies occurring during almitrine therapy had only a few weeks follow-up after having stopped the drug. We have studied clinical and electrophysiological data 6 to 12 months after almitrine had been given up in 9 patients from a group of 14 whose
In rats of different ages, acute severe hypoglycemia with isoelectric EEG induced extensive deterioration of the energy state and gross alteration of amino acid contents. During recovery of adult animals, tissue glucose concentration returned to normal, while the rate of glycogen synthesis was slow,
On rat cerebral and cerebellar cortex, severe hypoglycemia with isoelectric EEG induced extensive deterioration of the energy state and gross alteration of amino acid contents. During recovery, tissue glucose concentration returned to normal, while the rate of glycogen synthesis was slow, both