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ricinine/ricinus

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Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis.

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The extract of the pericarp of castor bean (Ricinus communis) showed some typical central nervous system stimulant effects when administered to mice. The animals became exophthalmic, presented tremors and clonic seizures and died a few minutes after receiving larger doses of the extract. At lower

Translocation and Metabolism of Ricinine in the Castor Bean Plant, Ricinus communis L.

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Ricinine-3,5-(14)C (N-methyl-3-cyano-4-methoxy-2-pyridone) administered to senescent leaves of Ricinus communis L. was translocated to all other tissues of the plant. Developing fruit and especially seeds were found to be labeled the most rapidly. Young growing leaves and other developing tissues of

Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives.

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Ricinine (1), a known major alkaloid in Ricinus communis plant, was used as a starting compound for the synthesis of six ricinine derivatives; two new and four known compounds. The new derivatives; 3-amino-5-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one (2), and

Microwave-Assisted Extraction of Ricinine from Ricinus communis Leaves.

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Identifikohuni Regjistrohu
The alkaloid ricinine (3-cyano-4-methoxy-N-methyl-2-pyridone) is found in different parts of the Ricinus communis plant and is known to possess several bioactive properties, including strong antioxidant activity. In this study, a new microwave-assisted extraction (MAE) method was developed

Metabolism of the alpha-Pyridone Ring of Ricinine in Ricinus communis L.

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Chemically synthesized ricinine-3,5-(14)C was used to study the metabolism of this alkaloid in the plant which produces it, Ricinus communis L. In a time course study, ricinine-3,5-(14)C was administered to a series of castor plants (Ricinus communis L.) and the radioactivity recovered in the

High-speed counter-current chromatographic isolation of ricinine, an insecticide from Ricinus communis.

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The alkaloid ricinine, an insecticide for leaf-cutting ant (Atta sexdens rubropilosa), was obtained from Ricinus communis. A two-phase solvent system composed of CH(2)Cl(2)/EtOH/H(2)O (93:35:72, v/v/v) was used for high-speed counter-current chromatographic (HSCCC) isolation of ricinine in high
The focus of this study was the identification of compounds from plant extracts for use in crop protection. This paper reports on the toxic activity of fractions of leaf extracts of Ricinus communis L (Euphorbiaceae) and isolated active compounds in the leaf-cutting ant Atta sexdens rubropilosa

Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α.

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Wnt signaling plays important roles in proliferation, differentiation, development of cells, and various diseases. Activity-guided fractionation of the MeOH extract of the Ricinus communis stem led to the isolation of four compounds (1-4). The TCF/β-catenin transcription activities of 1 and 3 were

[NOTE ON RICININE, TOXIN FROM RICINUS SEEDS].

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Biosynthesis of Ricinine in Excised Roots of Ricinus communis.

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The pyridine nucleotide cycle and its role in the biosynthesis of ricinine by Ricinus communis L.

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Nicotinic Acid-Ricinine Relationship in Sterile Cultures of Ricinus communis L.

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Phytochemical investigation characterisation and anticonvulsant activity of Ricinus communis seeds in mice.

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Identifikohuni Regjistrohu
The ethanol extract of the dried, powdered hull portion of Ricinus communis seeds indicated the presence of alkaloids, steroids, flavonoids, glycosides and phenolics, amongst others. Ricinine was isolated as an active constituent and characterised by various chemical and spectroscopic techniques.

Review - Ricinus cmmunis - Ethnomedicinal uses and pharmacological activities.

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Identifikohuni Regjistrohu
Ricinus cmmunis L. (Castor oil plant) is an important medicinal plant belonging to family Euphorbiaceae. Its phytochemistry, biological and pharmacological activities, and ethnomedicinal uses have been reviewed in the present study. The reported chemical constituents showed the presence of
The analytical proof of a toxic mushroom and/or plant ingestion at an early stage of a suspected intoxication can be crucial for fast therapeutic decision making. Therefore, comprehensive analytical procedures need to be available. This study aimed to develop a strategy for the qualitative analysis
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