Investigators employ the recommendations of the American College of Sport Medicine and the World Health Organization for adults to divide our enrolled patients having moderate-intensity as 30-60 min∙d-1 (≥150 min∙wk-1 ) or vigorous-intensity as 20-60 min∙d-1 (≥75 min∙wk-1) for 6-8 weeks preoperatively.
The severity of postoperative pain are measured prospectively at 1, 4, 7, 10 and 24 hours after the surgical operations.
The operations are performed under inhalation general anesthesia with endotracheal intubation or through laryngeal mask.

No any moderate-intensity or vigorous-intensity physical activity for our enrolled patients preoperatively.
The severity of postoperative pain are measured prospectively at 1, 4, 7, 10 and 24 hours after the surgical operations.
Various types of operations are performed under inhalation general anesthesia with endotracheal intubation or through laryngeal mask.

Postoperative Pain

Physical Activity

Compare postoperative pain scores for the physical activity Vs non-physical activity group

Compare the severity of postoperative pain of the physical activity group Vs non-physical activity group

Can Physical Activities Reduce Postoperative Pain in Adults

Preoperative Moderate-to-vigorous Intensity Physical Activities Reduce Postoperative Pain in Adults

The pain scores different of the physical activity (PA) Vs non-physical activity (non-PA) groups are using the numeric pain rating scale (NRS) with 1 represent no pain and 5 represent the worst possible pain.
The severity of postoperative pain will be measured prospectively by using NRS at different postoperative time points (i.e. 1, 4, 7, 10, and 24 hour) for comparing the postoperative pain different between PA and non-PA patients.

Chiayi Christian Hospital

latent growth modeling using structural equation model,

Xiang-Sha-Liu-Jun-Zi-Tang at a rate of 3.0 g three times per day for 28 days

Placebo at a rate of 3.0 g three times per day for 28 days

Irritable Bowel Syndrome

Xiang-Sha-Liu-Jun-Zi-Tang at a rate of 3.0 g three times per day for 28 days. We use the Chinese herb for the treat of IBS patient

Xiang-Sha-Liu-Jun-Zi-Tang

Xiang-Sha-Liu-Jun-Zi-Tang at a rate of 3.0 g three times per day for 28 days. Placebo drug is 1/10 dose of experiment drug .

Placebo

China Medical University Hospital

A Study of Xiang-Sha-Liu-Jun-Zi-Tang in Patients With Irritable Bowel Syndrome

A Randomized Double Blind Placebo Control Study of Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT)in Patients With Irritable Bowel Syndrome

25 mg diphenhydramine IV administered before surgery

50 mg diphenhydramine IV administered before surgery

25 mg Diphenhydramine IV

50 mg Diphenhydramine IV

Total

Sex: Female, Male

Region of Enrollment

Scores on QOR (quality of recovery) 40 questionnaire.The QoR-40 score, which ranges from 40 to 200, representing very poor to outstanding quality of recovery, respectively.

Quality of Recovery 40 at 24 Hours

Overall Study

Gildasio De Oliveira MD

Surgery

Pain

.9 normal saline administered before surgery.

.9 normal saline

25 mg diphenhydramine IV

50 mg diphenhydramine administered IV before surgery

salvia officinalis/vomiting

Can Physical Activities Reduce Postoperative Pain in Adults

A Study of Xiang-Sha-Liu-Jun-Zi-Tang in Patients With Irritable Bowel Syndrome

A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory Surgery

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