virilism/edema

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Massive ovarian edema in a prepubertal girl without signs of virilization or early puberty.

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Massive ovarian edema is a rare cause of ovarian enlargement in young women. This article describes the case in a nine-year-old girl without signs of virilization or early puberty. The patient underwent laparotomy and a right oophorectomy was performed. The final pathology was massive ovarian edema.

Massive edema of the ovary and virilization.

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Endocrine studies of a virilized adolescent patient with massive ovarian edema are reported. The histologic features of the affected ovary consisted of diffuse edematous stroma with scattered islands of lutein-like cells and no evidence of recent ovulation. Plasma concentrations of progesterone and

Massive ovarian edema in a woman receiving clomiphene citrate. A case report.

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There have been 65 previously reported cases of massive ovarian edema. We present a case in a woman receiving clomiphene citrate. It is an uncommon, benign condition and usually involves the right ovary. Patients frequently present with intermittent abdominal pain, menstrual irregularities and

Massive ovarian edema with androgen secretion. A pathological and endocrine study with review of the literature.

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A case of massive edema of the left ovary with virilization is described. Microscopically, massive interstitial edema with luteinization of theca and stromal cells was found. A few stromal cells contained Reinke-type crystalloids--an original observation. Peripheral concentrations of testosterone,

Prenatal diagnosis for congenital adrenal hyperplasia in 532 pregnancies.

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Congenital adrenal hyperplasia (CAH) refers to a family of monogenic inherited disorders of adrenal steroidogenesis most often caused by enzyme 21-hydroxylase deficiency (21-OHD). In the classic forms of CAH (simple virilizing and salt wasting), androgen excess causes external genital ambiguity in

Current options for prophylactic treatment of hereditary angioedema in the United States: patient-based considerations.

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Hereditary angioedema (HAE) results from mutations in the C1-esterase inhibitor (C1 INH) gene that decrease production of C1 INH or render it dysfunctional. HAE is characterized by recurrent, unpredictable, bradykinin-mediated edema of the extremities, face, genitalia, trunk, gastrointestinal tract,

Pharmacological agents in pregnancy to improve fetal conditions: prevention of fetal cardiac insufficiency, consequences of congenital adrenal hyperplasia and respiratory distress syndrome.

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Identifikohuni Regjistrohu

Improved prenatal diagnostics of fetal diseases have made it necessary to evaluate and develop maternal pharmacological treatment programs to improve fetal condition. In fetal cardiac insufficiency due to persistent tachyarrhythmias, maternal treatment, e.g., with either digoxin alone or combined

Prenatal diagnosis and treatment of congenital adrenal hyperplasia.

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Identifikohuni Regjistrohu

Advances in technology have made possible the prenatal diagnosis and treatment of female fetuses with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hormonal measurement of 17-hydroxyprogesterone, androstenedione, testosterone and 21-deoxycortisol and HLA typing and DNA

Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report.

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BACKGROUND Mature, benign cystic teratomas of the ovary are common in reproductive-age women, but they are very rarely associated with androgen production and subsequent development of hirsutism or virilization. We describe a case of postmenopausal hirsutism and hyperandrogenism caused by a mature

Krukenberg tumors of the ovary: a clinicopathologic analysis of 120 cases with emphasis on their variable pathologic manifestations.

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120 Krukenberg tumors were analyzed with emphasis on their wide microscopic spectrum and resultant problems in differential diagnosis. The patients ranged from 13 to 84 years (average, 45 years) with 43% of them under 40 years. Abdominal swelling or pain usually accounted for the clinical

Granulosa cell, Sertoli-Leydig cell, and unclassified sex cord-stromal tumors associated with pregnancy: a clinicopathological analysis of thirty-six cases.

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Seventeen granulosa cell, thirteen Sertoli-Leydig cell and six unclassified sex cord-stromal tumors diagnosed during pregnancy or the puerperium were reviewed. Eleven patients presented with abdominal pain or swelling, five in shock, two with virilization, and one with vaginal bleeding. Three

Benefits and risks of danazol in hereditary angioedema: a long-term survey of 118 patients.

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Identifikohuni Regjistrohu

BACKGROUND Hereditary angioedema (HAE) due to C1 inhibitor deficiency is clinically characterized by relapsing skin swellings, abdominal pain attacks, and life-threatening upper airway obstruction. Treatment with androgens prevents attacks for those with this condition. OBJECTIVE To examine the

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