Saikosaponin homologues from Clinopodium spp. The structures of clinoposaponins XII-XX.
Кључне речи
Апстрактан
Nine new saikosaponin homologues, called clinoposaponins XII-XX, were isolated from the aerial parts of Clinopodium vulgare, C. chinense and C. chinense var. parviflorum together with nine known saikosaponin homologues. On the basis of spectral and chemical evidence, the structures of clinoposaponins XII-XX were determined to be 3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl] saikogenin F, 3-O-beta-D-fucopyranosyl-21 beta- hydroxysaikogenin F, 3-O-[beta-D-glucopyranosyl-(1--> 3)-beta-D-fucopyranosyl]-21 beta-hydroxysaikogenin F, 3-O-[beta-D- glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]saikogenin F, 3-O-[beta-D-glucopyranosyl-(1-->2)-[beta-D-glucopyranosyl- (1-->3)]-beta-D-fucopyranosyl]-21 beta-hydroxysaikogenin F, 3-O-[beta-D-glucopyranosyl-(1-->2)-[beta-D-glucopyranosyl- (1-->3)]-beta-D-fucopyranosyl]-23-oxosaikogenin E, 3-O- [beta-D-glucopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->3)]-beta- D-fucopyranosyl]-16-ketosaikogenin F, 3-O-[beta-D-glucopyranosyl-(1--> 2)-[beta-D-glucopyranosyl-(1-->3)]-beta-D-fucopyranosyl]-30-hydroxysa ikogenin F, 3-O-[beta-D-glucopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->3)] -beta-D-fucopyranosyl]-30-oxo-saikogenin F, respectively. The known saponins were assigned to be clinoposaponins III, V, IX, X, XI, buddlejasaponins I, IV, 3-O-beta-D-fucopyranosylsaikogenin F and saikosaponin a.
