[Studies on chemical constituents in root of Phlomis medicinalis I].
Кључне речи
Апстрактан
OBJECTIVE
To study the chemical constituents in root of Phlomis medicinalis.
METHODS
The compounds were isolated and repeatedly purified on macroporous resin, silica gel column chromatography, TLC and Prep-HPLC and the structures were elucidated by physico-chemical properties and NMR spectra.
RESULTS
Eight compounds were obtained and elucidated as 5-Hydroxy-7-methoxy-4, 6-dimethylphthalide (1), 4-hydroxymethyl-2-furaldehyde (2) and six iridoid glucosides: 6-O-acetyl-shanzhiside methyl ester (3), 8-O-acetyl-shanzhiside methyl ester (4), shanzhiside methyl ester (5), sesamoside (6), phloyoside II (7) and dehydropentstemoside (8).
CONCLUSIONS
All the compounds were isolated from the plant for the first time and 1 and 3 were obtained from the plants of Phlomis for the first time.
