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acidic peptide/рак
Веза се чува у привремену меморију
Страна 1 од 37 резултати
Method of treating cancer with a 43 kD human cancer antigen
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The present invention relates generally to the field of immunotherapy based on the identification and isolation of human tumor antigens. In particular embodiments, the invention also relates to the use of human monoclonal antibodies to isolate the epitopic sequence of a tumor-associated antigen.
Immunoreactive peptide sequence from a 43 KD human cancer antigen
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the field of immunotherapy based on the identification and isolation of human tumor antigens. In particular embodiments, the invention also relates to the use of human monoclonal antibodies to isolate
Methods for enhancing an immune response from a 43 KD human cancer antigen
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The present invention relates generally to the field of immunotherapy based on the identification and isolation of human tumor antigens. In particular embodiments, the invention also relates to the use of human monoclonal antibodies to isolate the epitopic sequence of a tumor-associated antigen.
Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
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FIELD OF THE INVENTION
The present invention relates to the area of cancer diagnostics and therapeutics. More specifically, the invention relates to the isolation and purification of a novel cancer peptide and an alternative open reading frame DNA sequence encoding the cancer peptide. The invention
Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
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FIELD OF THE INVENTION
The present invention relates to the area of cancer diagnostics and therapeutics. More specifically, the invention relates to the isolation and purification of a novel cancer peptide and an alternative open reading frame DNA sequence encoding the cancer peptide. The invention
Peptide-conjugates that bind to VEGF-stimulated or tumor vasculature and methods of treatment
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BACKGROUND OF THE INVENTION
During tumor progression, tumor cells require more oxygen and metabolites to remove waste products. In addition gaining access to the host vascular system and generation of a tumor blood supply are rate-limiting steps for tumor progression (Bergers et al., 2003).
Pharmaceutical composition which inhibits the growth of a tumor
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BACKGROUND OF THE INVENTION
A great number of pharmaceutically active ingredients are known in the art which inhibit the growth of tumor-cells, respectively kill tumor-cells or leukaemia cells. Usually, however, said active ingredients also inhibit to a certain extent the growth of the healthy
Genetic Markers for breast, ovarian, and prostatic cancer
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INTRODUCTION
1. Field of the Invention
The field of the invention is genetic markers for inheritable breast cancer susceptibility.
2. Background
The largest proportion of inherited breast cancer described so far has been attributed to a genetic locus, the BRCA1 locus, on chromosome 17q21 (Hall et
Genetic markers for breast, ovarian, and prostatic cancer
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INTRODUCTION
FIELD OF THE INVENTION
The field of the invention is genetic markers for inheritable breast cancer susceptibility.
BACKGROUND
The largest proportion of inherited breast cancer described so far has been attributed to a genetic locus, the BRCA1 locus, on chromosome 17q21 (Hall et al. 1990
Lung cancer-targeted peptides and applications thereof
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BACKGROUND OF THE INVENTION
Lung cancer is the leading cause of cancer-related mortality in the world. The five-year survival rate is less than 15% for patients with advanced non-small cell lung cancer (NSCLC). Lack of tumor specificity remains a major problem for chemotherapies in which side
Cytotoxic boronic acid peptide analogs
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FIELD OF THE INVENTION
This invention relates to boron analogs of amino acids and small peptides and the use of the analogs to inhibit growth or colony formation of mammalian cells. More specifically, the present invention relates to methods to prepare boronic acid analogs of tripeptides or
Cytotoxic boronic acid peptide analogs
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FIELD OF THE INVENTION
This invention relates to boron analogs of amino acids and small peptides and the use of the analogs to inhibit growth or colony formation of mammalian cells. More specifically, the present invention relates to methods to prepare boronic acid analogs of tripeptides or
Boron analogs of amino acid/peptide protease inhibitors
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BACKGROUND OF THE INVENTION
This invention was made with government support under grant CA 09441 awarded by the National Cancer Institute. The government of the United States has certain rights in this invention.
This invention relates to boron analogs of amino acids and small peptides and the use
Nucleic acid of novel human kinesin-related gene protein encoded by the nucleic acid peptide fragment thereof and anticancer agents comprising the nucleic acid and the like
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CROSS-REFERENCED APPLICATION
This application is a National phase of International Application PCT/JP01/08635, filed Oct. 1, 2001, which designated the U.S. and that International Application was not published under PCT Article 21(2) in English.
1. Technical Field
This invention relates to novel
Growth factor binding molecules
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3. FIELD OF INVENTION
The present invention relates generally to a family of synthetic molecules capable of binding to growth factors. More particularly, the invention relates to agents that bind growth factors through a plurality of peptide loops attached to a non-peptide, organic scaffold. The
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