6 резултати
This invention relates to novel substituted benzamides having useful pharmacological properties, to pharmaceutical compositions containing them, and to a process for their preparation.
N-(2-Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide and 1-ethyl-2(2-methoxy-5-sulphamoylbenzamidomethyl)
This invention relates to novel compounds, to pharmaceutical compositions containing them, and to a process for their preparation.
European Patent Application No. 79302978.6 and U.S. Pat. No. 4273778 disclose that compounds of the formula (A), and pharmaceutically acceptable salts thereof: ##STR2##
SUMMARY OF THE INVENTION
This invention relates to novel substituted benzamides of the formula ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and A are as defined below, which are useful in the treatment of emesis, particularly chemotherapy-induced emesis, such as cisplatin treatment
This invention relates to novel substituted benzamides having useful pharmacological properties, to pharmaceutical compositions containing them, and to a process for their preparation.
N-(2-Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide,
BACKGROUND OF THE INVENTION
(1) Field of the Invention
This invention relates to novel substituted benzamides having useful pharmacological properties, to pharmaceutical compositions containing them, and to a method for their use.
(2) Description of the Prior Art
U.S. Pat. No. 3,177,252 describes
SUMMARY OF THE INVENTION
According to one aspect of our invention, we provide compounds of the general formula ##STR1## wherein R represents a lower alkoxy or lower alkenyloxy group; R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, or a