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cachexia/повраћање

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9 резултати

Sulphonamide derivatives, their preparation and their therapeutic application

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FIELD OF THE INVENTION The present invention relates to sulfonamide derivatives, to the process for preparing them and to their therapeutic use. BACKGROUND OF THE INVENTION Orexins A and B (or hypocretins 1 and 2) are hypothalamus neuropeptides of 33 and 28 amino acids, respectively, recently

Method for the management of cancer and cancer treatment-related comorbidities

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TECHNICAL FIELD The invention concerns a method for the management of cancer and treatment cancer comorbidities, including but not limited to cancer-related fatigue, cachexia, anorexia, pain, anemia, asthenia, depression, impaired cognitive function, loss of appetite, muscle weakness, nausea,

Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders

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FIELD OF THE INVENTION The present invention relates to novel conformationally-defined macrocyclic compounds that bind to and/or are functional modulators of the motilin receptor including subtypes, isoforms and/or variants thereof. These macrocyclic compounds possess appropriate pharmacological

Acid-modified arabinogalactan protein composition

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to arabinogalactans. In particular, this invention relates to an acid-modified arabinogalactan protein composition, having an arabinose:galactose ratio of less than 3.5:1 or less than 80% of the arabinose:galactose ratio of

Urea compounds and their use as enzyme inhibitors

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FIELD OF THE INVENTION The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty

Urea compounds and their use as enzyme inhibitors

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FIELD OF THE INVENTION The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty

Transdermal cannabinoid formulations

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CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority to pending U.S. application Ser. No. 14/561,091 entitled "Transdermal Cannabinoid Formulations", filed Dec. 4, 2014, now U.S. Pat. No. 9,375,417, issued Jun. 28, 2016, the disclosure of which is hereby incorporated by reference

Transdermal cannabinoid formulations

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BACKGROUND The clinical usefulness of the cannabinoids, including 11.sup.9-tetrahydrocannabinol (/1.sup.9-THC), to provide analgesia, help alleviate nausea and emesis, as well as stimulate appetite has been well-recognized. Cannabinoids offer a variety of pharmacological benefits, including, but not

Transdermal cannabinoid formulations

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BACKGROUND The clinical usefulness of the cannabinoids, including .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC), to provide analgesia, help alleviate nausea and emesis, as well as stimulate appetite has been well-recognized. Cannabinoids offer a variety of pharmacological benefits,
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