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colchicine/мучнина

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Death following colchicine poisoning.

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A 45-year-old male was admitted to hospital after 2 to 3 days of vomiting, nausea, and diarrhea following an apparent overdose of colchicine tables. During hospitalization his white blood cell count fell dramatically. At death, 33 h following initial hospitalization, pleural effusion with bilateral

Acute colchicine intoxication complicated with complete AV block.

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Colchicine, is an old and well-known drug, used for treatment of rheumatic diseases. Nausea, vomiting, abdominal pain, and diarrhea are the clinical symptoms of colchicine poisoning. Cardiotoxicity can lead to mortality. We report a case of colchicine intoxication complicated with complete heart

Fatal poisoning in children: acute colchicine intoxication and new treatment approaches.

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BACKGROUND Colchicine poisoning is potentially life-threatening. Deaths generally result from hypovolemic shock and cardiovascular collapse or secondary to rapidly progressive multiorgan failure. OBJECTIVE The purpose of this study is to discuss the clinical effects, treatments and outcomes of

Evaluation of the Colchicine Poisoning Cases in a Pediatric Intensive Care Unit: Five Year Study.

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BACKGROUND Colchicine poisoning is an uncommon but serious form of drug intoxication. It may produce life-threatening systemic effects. In toxic doses it produces nausea and vomiting and bone marrow suppression, often leading to sepsis, hypocalcemia, adult respiratory distress syndrome, and direct

Epithelial cell mitotic arrest--a useful postmortem histologic marker in cases of possible colchicine toxicity.

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Following ingestion of 30 mg of presumed benztropine (Cogentin) a 39-year-old male developed nausea, vomiting and diarrhea. His admission to hospital was soon followed by collapse and death. Histological examination, however, revealed increased numbers of mitotic figures in otherwise normal

Treatment of pustulosis palmaris et plantaris with oral doses of colchicine.

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The effect of oral doses of colchicine on pustule formation was studied in 32 patients with pustulosis palmaris et plantaris without associated psoriasis. Oral administration of colchicine, 1 to 2 mg daily, was started during periods of disease exacerbation, and the dosage was gradually decreased to

Colchicine is an effective treatment for patients with chronic constipation: an open-label trial.

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Chronic constipation is a common clinical condition that frequently does not respond to routine therapeutic measures. We hypothesized that colchicine would be effective in this condition because we reported that it stimulates intestinal motility in rats and commonly causes diarrhea in patients

Biomechanical measurement and analysis of colchicine-induced effects on cells by nanoindentation using an atomic force microscope.

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Colchicine is a drug commonly used for the treatment of gout, however, patients may sometimes encounter side-effects induced by taking colchicine, such as nausea, vomiting, diarrhea and kidney failure. In this regard, it is imperative to investigate the mechanism effects of colchicine on biological

Clinical Manifestations and Outcomes of Colchicine Poisoning Cases; A Cross Sectional Study

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Introduction: Colchicine is a medication with narrow therapeutic index, leading to both accidental and suicidal poisonings incidents. This study aimed to investigate the clinical and laboratory manifestations, as well as outcomes of colchicine poisoning patients

Colchicine poisoning.

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Colchicine poisoning is an unusual but serious form of drug intoxication. Although relatively uncommon, colchicine poisoning may produce life-threatening systemic effects that must be recognized and treated by the emergency physician. This alkaloid found in Colchicum autumnale is used primarily in

Colchicine for acute gout.

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BACKGROUND This is an update of a Cochrane review first published in 2006. Gout is one of the most common rheumatic diseases worldwide. Despite the use of colchicine as one of the first-line therapies for the treatment of acute gout, evidence for its benefits and harms is relatively

Fatal colchicine poisoning by accidental ingestion of Colchicum persicum: a case report.

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Colchicine poisoning can occur not only by taking dosage form but also by ingesting a plant containing colchicine. A 39-year-old man presented to the emergency room with nausea, vomiting, and diarrhea 9 hours after ingestion of wild garlic. Symptoms attributed to food poisoning, and he received

Colchicine poisoning resulting from accidental ingestion of meadow saffron (Colchicum autumnale).

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A rare case of colchicine poisoning resulting from accidental ingestion of meadow saffron (Colchicun Autumnale) is reported. The plant can frequently be found in the woods of the Northern Hemisphere (1), also in Japan. A 48-year-old male was admitted to hospital complaining of vomiting, nausea and

Dangers of low-dose colchicine in patients with renal failure.

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(1) Life-threatening colchicine intoxication can occur in patients with renal failure, even with low-dose regimens. (2) Diarrhoea, nausea and vomiting are the first manifestations of overdose. Colchicine must be withdrawn immediately to avoid severe complications (especially haematological and

Colchicine intoxication: a report of two suicide cases.

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Colchicine, an old and well-known drug, is an alkaloid extracted from Colchicum autumnale and related species. Colchicine inhibits the deposition of uric acid crystals and is an inhibitor of mitosis. Nausea, vomiting, abdominal pain, and diarrhea, with a massive loss of fluid and electrolytes are
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