12 резултати
BACKGROUND
Colorectal cancer is a common form of cancer, the incidence of which is increasing worldwide. Various methods, including fecal occult blood test and colonoscopy, are currently used for screening colorectal cancer and have increased the rates of detection for early-stage cancer. Colorectal
SEQUENCE LISTING
The instant application contains a sequence listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jan. 20, 2018, is named 218107_0003_03_US_ST25.txt and is 45,280 bytes in size.
BACKGROUND OF
BACKGROUND OF THE INVENTION
The sequence listing that is contained in the file named "GGEOP0004USD2_ST25.txt", which is 45 KB (as measured in Microsoft Windows.RTM.) and was created on Feb. 10, 2016, is filed herewith by electronic submission and is incorporated by reference herein.
1. Field of the
The sequence listing that is contained in the file named "GGEOP0004USD1_ST25.txt", which is 45 KB (as measured in Microsoft Windows.RTM.) and was created on Mar. 21, 2014, is filed herewith by electronic submission and is incorporated by reference herein.
BACKGROUND OF THE INVENTION
1. Field of the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention generally relates to compositions and methods for the treatment of cancer with enzymes that deplete L-Methionine. More particularly, it concerns the engineering of a novel human methionine-.gamma.-lyase enzyme with methionine
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns an improved human methionine-.gamma.-lyase (hMGL) for use in the treatment of cancer.
2. Description of Related Art
The demand for the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns an improved human methionine-.gamma.-lyase (hMGL) for use in the treatment of cancer.
2. Description of Related Art
The demand for the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns an improved human methionine-.gamma.-lyase (hMGL) for use in the treatment of cancer.
2. Description of Related Art
The demand for the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns an improved human methionine-.gamma.-lyase (hMGL) for use in the treatment of cancer.
2. Description of Related Art
The demand for the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns compositions and methods for the treatment of cancer with enzymes that deplete both L-cystine and L-cysteine. Even more particularly, it
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of medicine and biology. More particularly, it concerns compositions and methods for the treatment of cancer with enzymes that deplete both L-cystine and L-cysteine. Even more particularly, it
BACKGROUND
Certain embodiments are directed to the fields of chemistry and medicine. Certain aspects are directed to compounds for treating chronic pancreatitis, colon cancer, or liver fibrosis.
Chronic pancreatitis (CP) is a progressive, non-curable disorder of the pancreas (Schneider and Whitcomb,