dark/hypoxia

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Illuminating the dark depths inside coral.

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The ability to observe in situ 3D distribution and dynamics of endosymbionts in corals is crucial for gaining a mechanistic understanding of coral bleaching and reef degradation. Here, we report the development of a tissue clearing (TC)-coupled light sheet fluorescence microscopy (LSFM) method for

Dark adaptation during systemic hypoxia induced by chronic respiratory insufficiency.

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OBJECTIVE To investigate dark adaptation during hypoxia in patients with chronic respiratory failure. METHODS At three visits, dark adaptation was recorded by computerized dark adaptometry in 13 patients with chronic respiratory insufficiency treated by long-term oxygen therapy. At visits 1 and 3,

Effects of anoxia, oxygen, and increased intrapulmonary pressure on dark adaptation.

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I. Impaired dark adaptation in symptomatic carotid artery disease.

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It has been known for more than a century that even slight hypoxemia reduces dark adaptation. We studied dark adaptation in symptomatic carotid artery disease. Twenty-one consecutive patients scheduled for first-time carotid endarterectomy and 31 age-matched control subjects with normal carotid

Photo-bleaching of Chlamydomonas reinhardtii after dark-anoxic incubation.

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In aerobes, anoxia impairs mitochondrial energy generation as well as biosynthesis and degradation of essential cell components. In a recent analysis we have shown that the unicellular green alga Chlamydomonas reinhardtii responds to anaerobiosis in the dark by significant changes of the

Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons.

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In the rat cerebellar slice preparation, exposure to hypoxia elicited by a 30 min exposure to artificial cerebrospinal fluid continuously gassed with 95% N(2): 5% CO(2) induced a characteristic type of toxicity of Purkinje cells (PCs) resembling excitotoxic-mediated dark cell degeneration (DCD).

Genetic instability: the dark side of the hypoxic response.

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Under low oxygen tension, the activated transcription factor HIF-1alpha upregulates an array of hypoxia-inducible genes via heterodimerization with ARNT and binding to the hypoxia-responsive element in the promoter. Alternatively, HIF-1alpha regulates hypoxia-responsive genes by functionally

Cancer associated fibroblasts: the dark side of the coin.

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Valid experimental evidence has recently shown that progression of malignant tumors does not depend exclusively on cell-autonomous properties of the cancer cells, but is also deeply influenced by tumor stroma reactivity and undergoes a strict microenvironmental control. Beside structural

A novel device for assessing dark adaptation in field settings.

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BACKGROUND Aberrant dark adaptation is common to many ocular diseases and pathophysiological conditions, including vitamin A deficiency, cardiopulmonary diseases, and hypoxia. Scotopic vision and pupillary responsiveness have typically been measured using subjective, time-consuming methods. Existing

Aviation-related respiratory gas disturbances affect dark adaptation: a reappraisal.

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This study examined the time course of early scotopic threshold sensitivity during dark adaptation under mild to moderate hypoxia, moderate hypocapnia and hyperoxia, measuring detection time displacement relative to normoxia. Cone rod inflection and early rod adaptation were highlighted using

Dark Adaptation at High Altitude: An Unexpected Pupillary Response to Chronic Hypoxia in Andean Highlanders.

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Healy, Katherine, Alain B. Labrique, J. Jaime Miranda, Robert H. Gilman, David Danz, Victor G. Davila-Roman, Luis Huicho, Fabiola León-Velarde, and William Checkley. Dark adaptation at high altitude: an unexpected pupillary response to chronic hypoxia in Andean highlanders. High Alt Med Biol.

Mechanotransduction in tumor progression: The dark side of the force.

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Cancer has been characterized as a genetic disease, associated with mutations that cause pathological alterations of the cell cycle, adhesion, or invasive motility. Recently, the importance of the anomalous mechanical properties of tumor tissues, which activate tumorigenic biochemical pathways, has

Copper response regulator1-dependent and -independent responses of the Chlamydomonas reinhardtii transcriptome to dark anoxia.

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Anaerobiosis is a stress condition for aerobic organisms and requires extensive acclimation responses. We used RNA-Seq for a whole-genome view of the acclimation of Chlamydomonas reinhardtii to anoxic conditions imposed simultaneously with transfer to the dark. Nearly 1.4 × 10(3) genes were affected

The Effect of Anoxemia on Dark Adaptation in the Normal and Vitamin A Deficient Subject.

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Dark Stomatal Movement in Sunflowers in Response to Illumination under Nitrogen.

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Experiments were performed on intact sunflowers (Helianthus annuus) placed in a specially designed experimental chamber which allows instantaneous modifications of the atmospheric composition without changing any other conditions. After one night in normal conditions, the plant was illuminated under

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