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Biotransformation profiles from a cohort of chronic fatigue women in response to a hepatic detoxification challenge.

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Chronic fatigue, in its various manifestations, frequently co-occur with pain, sleep disturbances and depression and is a non-communicable condition which is rapidly becoming endemic worldwide. However, it is handicapped by a lack of objective definitions and diagnostic measures. This has prompted

Detoxification process for glutaraldehyde-treated bovine pericardium: biological, chemical and mechanical characterization.

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OBJECTIVE Glutaraldehyde cross-linked bovine pericardium was post-treated with homocysteic acid in order to bond unreacted glutaraldehyde groups, and preserved in aldehyde-free solution to reduce the toxicity and calcification potential of the tanned tissue. The study aim was to verify the efficacy

Results of dental amalgam removal and mercury detoxification using DMPS and neural therapy.

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Sixty consecutive patients who had undergone replacement of dental amalgam fillings and a protocol of nutritional support and heavy metal detoxification using dimercapto-propanyl-sulfate and neural therapy were surveyed. A questionnaire was mailed to the patients and 42 responded, resulting in a

Songwriting to Target State Shame, Guilt, and Pride in Adults with Substance Use Disorder on a Detoxification Unit: A Cluster-Randomized Study.

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Resultant of engaging in behaviors outside of their value systems to maintain addiction, many people with substance use disorder (SUD) feel shame and guilt. Although shame, guilt, and pride do not represent traditional dependent measures in SUD research, experimental studies targeting

Complaints that predict drop-out from a detoxification and counselling unit.

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Sixty-one consecutive clients in a multidrug addiction detoxification and counselling unit were interviewed by their medical counsellor about bodily pain, distress, and coherence in their life. Clients who did not complete the 3-week postdetoxification program reported a higher level of fatigue and

Affect dimensions of male heroin addicts admitted for inpatient detoxification.

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The Profile of Mood States was administered to 197 male heroin addicts seeking inpatient detoxification. A principal factor analysis of the men's self-ratings revealed four major dimensions-Fatigue-inertia, Confused-depression, Anger-hostility, and Friendliness; these dimensions were similar to

Neurobehavioral dysfunction in firemen exposed to polycholorinated biphenyls (PCBs): possible improvement after detoxification.

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Fourteen firemen exposed to polychlorinated biphenyls (PCBs) and their byproducts generated in a transformer fire and explosion had neurophysiological and neuropsychological tests 6 mo after the fire. They were re-studied 6 wk later after undergoing 2-3 wk of an experimental detoxification program

[Suppression by ascorbic acid of neuromuscular fatigue due to sound-alcohol synergy].

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The interaction between effects of ethanol ingestion and those of infrasound on neuro-muscular fatigue in the animal is abolished by ascorbic acid. The relevant mechanism is in acetaldehyde detoxification.

Effects of citrulline supplementation on fatigue and exercise performance in mice.

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During high-intensity exercise, the concentration of ammonia is augmented in skeletal muscle. Ammonia activates phosphofructokinase and prevents oxidation of pyruvate to acetyl CoA, thus leading to exhaustion. Citrulline is an amino acid component of the urea cycle in the liver, along with ornithine

Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism.

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BACKGROUND Glutathione is an endogenous redox couple in animal cells and plays important roles in antioxidant defense and detoxification, although it is unknown if oral glutathione supplementation affects exercise-induced physiological changes. The present study investigated the effect of

A laboratory approach for characterizing chronic fatigue: what does metabolomics tell us?

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Manifestations of fatigue range from chronic fatigue up to a severe syndrome and myalgic encephalomyelitis. Fatigue grossly affects the functional status and quality of life of affected individuals, prompting the World Health Organization to recognize it as a chronic non-communicable

Sex hormones and alcohol withdrawal: does a good supply of testosterone prevent serious symptoms during detoxification?

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Owing to the clinical similarity between the male climacteric syndrome and the results of previous studies on the alcohol withdrawal syndrome in relation to sex hormones, we hypothesized that alcoholics with a poor supply of testosterone will develop more pronounced symptoms during alcohol

The detoxification enzyme systems.

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The human body is exposed to a wide array of xenobiotics in one s lifetime, from food components to environmental toxins to pharmaceuticals, and has developed complex enzymatic mechanisms to detoxify these substances. These mechanisms exhibit significant individual variability, and are affected by

A Detoxification Intervention for Gulf War Illness: A Pilot Randomized Controlled Trial.

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Approximately 30% of the 700,000 US veterans of the 1990-1991 Persian Gulf War developed multiple persistent symptoms called Gulf War illness. While the etiology is uncertain, several toxic exposures including pesticides and chemical warfare agents have shown associations. There is no effective

Negative moods correlate with craving in female methamphetamine users enrolled in compulsory detoxification.

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BACKGROUND Methamphetamine (METH) use, especially in females, has become a growing public health concern in China. In this study, we aimed to characterize the factors that contributed to drug craving in female METH users under isolated compulsory detoxification. We characterized factors contributing

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