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Страна 1 од 194 резултати
Hypoxia inducible factor-1α (HIF-1α) and some HIF-1 target genes are elevated in experimental glaucoma.
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Low levels of hypoxia have been suggested to be a mechanism of retinal damage in glaucoma. To test the hypothesis that the activation of the hypoxia-responsive transcription factor hypoxia inducible factor-1alpha (HIF-1alpha) is involved in the pathophysiology of glaucoma, we used a rat model of
[Ischemia and hypoxia. An attempt to explain the different rates of retinal ganglion cell death in glaucoma].
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In hypoxic or ischemic states, the receptors of the ganglion cells are overstimulated by release of neurotransmitters. Glutamate and GABA (gamma-aminobutyric acid) are the decisive neurotransmitters in the retina. It is presumed that the extent of cell death depends on the degree of depolarization,
Investigations into Hypoxia and Oxidative Stress at the Optic Nerve Head in a Rat Model of Glaucoma.
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The vascular hypothesis of glaucoma proposes that retinal ganglion cell axons traversing the optic nerve head (ONH) undergo oxygen and nutrient insufficiency as a result of compromised local blood flow, ultimately leading to their degeneration. To date, evidence for the hypothesis is largely
Potential metabolic markers in glaucoma and their regulation in response to hypoxia.
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Role of hypoxia-inducible factor-1α in preconditioning-induced protection of retinal ganglion cells in glaucoma.
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OBJECTIVE
We recently demonstrated in a mouse model of glaucoma that endogenous epigenetic mechanisms can be activated by a repetitive hypoxic preconditioning (RHP) stimulus to provide robust retinal ganglion cell (RGC) protection. Although we also provided evidence that RHP prevents or delays the
[Oxygen deficiency as 1 of the pathogenetic factors in cerebral cortical bioelectrical activity disorder in glaucoma].
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Rubeotic glaucoma.
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The literature of theories of causation of rubeosis and thrombotic glaucoma is briefly reviewed and attention is drawn to the fact that the causative role of anoxia of the retina, leading secondarily to rubeosis of the iris and subsequent glaucoma, was first described in 1954. After that attempts
Role of mammalian target of rapamycin in regulating HIF-1α and vascular endothelial growth factor signals in glaucoma.
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Hypoxia inducible factor subtype 1α (HIF-1α) in retinal tissues is involved in the development of glaucoma. This study examined the role played by mammalian target of rapamycin (mTOR) in regulating expression of HIF-1α and its downstream pathway, vascular endothelial growth factor (VEGF). Glaucoma
[Dynamics of vascular changes in neovascular glaucoma. I. Development of rubeosis iridis after cryosurgery].
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The author is evaluating the influence of two cryosurgical methods for the development of the rubeosis of iris in neovascular glaucoma. The cyclocryocoagulation was used as a single method in 12 eyes, the combination of transscleral panretinal cryocoagulation and cyclocryocoagulation in 26 eyes. The
[Nocturnal measurements of intraocular pressure in patients with normal-tension glaucoma and sleep apnea syndrome].
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BACKGROUND
About half of all normal-tension glaucoma patients and about one third of all primary open-angle glaucoma patients have sleep apnea syndrome. If sleep apnea syndrome causes some cases of glaucoma, the optic nerve damage could result from repetitive nocturnal hypoxias or from repetitive
[Expression of erythropoietin in neovascular glaucoma and its role in the angiogenesis in vitro].
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Objective: To explore the expression of erythropoietin (EPO) in neovascular glaucoma (NVG) and its role in the angiogenesis in vitro. Methods: The levels of EPO in aqueous humor and vitreous body of NVG patients (10 cases) and non-NVG patients (10 cases) were detected by enzyme-linked immunosorbent
Metalloproteinase 9 and TIMP-1 expression in retina and optic nerve in absolute angle closure glaucoma.
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OBJECTIVE
Glaucoma is one of the most important reason causes of the blindness, associated with retinal ganglion cells (RGC) death. This process is not fully understood, however apoptosis due to hypoxia is one of the most important processes leading to RGC death. Glaucomatous optic neuropathy is
Effect of simulated altitude on the visual fields of glaucoma patients and the elderly.
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We investigated whether mild hypoxia, such as may be encountered in civilian aircraft, causes temporary visual field defects in elderly persons or temporarily increases pre-existing defects in persons with glaucoma. The central 24-2 program on the Humphrey automated perimeter was used to test visual
Rubeosis iridis and neovascular glaucoma: II. Our own experiences with the treatment by cryocoagulation.
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The author evaluates the effect of two cryosurgical methods on the development of rubeosis iridis in neovascular glaucoma. In 12 eyes, cyclo-cryocoagulation was used as a single method, in 26 eyes, trans-scleral panretinal cryocoagulation was used in combination with cyclo-cryocoagulation in one
Some new data on the mechanism of the oxygen metabolism kinetics error in glaucoma.
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The paper presents the results of the study on oxygen metabolism in glaucoma patients. In the study a combined method, including oxyhemography and polarography, was used: a) for the determination of the tissue oxygen absorbtion constant (TOAC); and b) for the determination of the blood oxygen
Најкомплетнија база лековитог биља подржана науком
- Ради на 55 језика
- Биљни лекови потпомогнути науком
- Препознавање биљака по слици
- Интерактивна ГПС мапа - означите биље на локацији (ускоро)
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