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hydroxycoumarin/otok
Веза се чува у привремену меморију
7 резултати
Investigation of the dose-response relationship upon intraperitoneal administration of coumarin and 7-hydroxycoumarin on the carrageenan induced edema of the rat hind paw.
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The dose-response relationship upon intraperitoneal administration of coumarin (C) and 7-hydroxycoumarin (7HC) in rats was evaluated using the carrageenan induced edema of the hind paw. In a preliminary study C was indicated to reduce the 4-h edema at doses of 10 to 60 mg/kg i.p. Doses of 2.5 and 5
Mechanisms involved in the antinociceptive effects of 7-hydroxycoumarin.
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7-Hydroxycoumarin (umbelliferone, 1), the main metabolite of coumarin, has been reported to produce potent antinociceptive effects in animal models of pain. However, the biochemical events involved in antinociception mediated by 1 are currently not well understood. In the present study, the
Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
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Substituted hydroxycoumarins and 7- or 8-hydroxybenzo[f]coumarins were prepared by the treatment of phenols and naphthalenediols, respectively, with malic acid and H(2)SO(4) under microwave irradiation. 7- or 8-Hydroxybenzo[f]coumarins and 6-hydroxybenzo[h]coumarin were synthesized by the reaction
The effect of coumarin and 7-hydroxycoumarin on in vitro macrophage phagocytosis of latex particles.
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The influence of various concentrations of coumarin (C) and 7-Hydroxycoumarin (7HC) upon in vitro macrophage phagocytosis of latex particles was investigated. A C dose of 20 micrograms/ml was indicated to have the greatest stimulating effect of all doses used with a percent effect of 25.6. A C dose
Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom.
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Flavonoids, coumarins and other polyphenolic compounds are powerful antioxidants both in hydrophilic and lipophylic environments with diverse pharmacological properties including anti-inflammatory activity. Despite being widely used as powerful therapeutic agents for blood coagulation disorders,
Antiphlogistic and antipyretic activity of Peucedanum ostruthium.
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Extracts from the roots of Peucedanum ostruthium (L.) Koch were investigated for their antiphlogistic and antipyretic effects as well as for their influence on arachidonic acid metabolism. On carrageenan-induced rat paw edema, oral administration of 10% ethanolic extracts led to a marked inhibition
An insight into the therapeutic applications of coumarin compounds and their mechanisms of action
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The coumarins are heterocyclic compounds belonging to the class of benzopyrone enriched in various plants like tonka beans. Coumarins and their derivatives exert a vast array of bioactive properties such as anticoagulant, antibacterial, anti-inflammatory, antioxidant, antitumor, antiviral, and
Најкомплетнија база лековитог биља подржана науком
- Ради на 55 језика
- Биљни лекови потпомогнути науком
- Препознавање биљака по слици
- Интерактивна ГПС мапа - означите биље на локацији (ускоро)
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