hyperlipidemias/tyrosine

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Protein tyrosine phosphatase inhibitors and methods of use thereof

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FIELD OF THE INVENTION This invention relates to the field of protein tyrosine phosphatase inhibition. BACKGROUND OF THE INVENTION This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B. Reversible protein tyrosine phosphorylation, coordinated by the

Protein tyrosine phosphatase inhibitors and methods of use thereof

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1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase)

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This application is the National Stage of Application No. PCT/EP2006/046543, filed on Dec. 6, 2006, which claims benefit under 35 U.S.C. .sctn.119(a-d) of U.S. Provisional Application No. 60/748,491, filed Dec. 8, 2005, the contents of which are incorporated herein by reference in their

Oxindole hydrazide modulators of protein tyrosine phosphatases (PTPs)

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FIELD OF THE INVENTION The present invention is related to the use of oxindole hydrazide derivatives of formula (I) for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin

Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs)

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FIELD OF THE INVENTION The present invention is related to substituted methylene amide derivatives of formula (I), in particular for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose

Weight control product and method of treating hyperlipidemia and increasing vigor with said product

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FIELD OF THE INVENTION This invention relates generally to a weight control product that is administered enterally to mammals in need of losing weight and/or reducing the blood plasma lipid levels. The weight control product comprises a mixture of guggul extract and phosphate salts. The inventive

Aromatic farnesyl compound and application thereof

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REFERENCE TO CORRESPONDING APPLICATIONS The present application is the 371 national stage application based on International Application No. PCT/CN2015/097938, filed Dec. 18, 2015, which claims priority to Chinese Patent Application No. 20151057895.1, filed Sep. 11, 2015, Chinese Patent Application

Azole compound and medicinal use thereof

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TECHNICAL FIELD The present invention relates to a novel azole compound, more particularly, the present invention relates to an azole compound or a pharmaceutically acceptable salt thereof having a protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, and a pharmaceutical composition

Depsipeptides and drugs containing the same as the active ingredient

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TECHNICAL FIELD This invention relates to a novel depsipeptide and a pharmaceutical preparation containing the same as an active ingredient. The depsipeptides of the invention have a promoting activity on the production of apolipoprotein E, and they are useful as a therapeutic agent for neurologic

1-orthofluorophenyl substituted 1,2,5-thiazolidinedione derivatives as PTP-as inhibitors

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The present invention relates to thiadiazolidinone derivatives, pharmaceutical compositions containing such compounds, methods of making such and methods of treating conditions mediated by protein tyrosine phosphatases by employing such compounds. Accordingly, the present invention provides

Organic compounds

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