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hypoxanthine/рак

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8 резултати

Compositions and methods for cancer management using antibodies binding to nucleotide salvage pathway enzymes and complexes thereof

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BACKGROUND In 2007 it was reported that over half a million people died from cancer and more than 1.4 million new cases were diagnosed in the United States. Thus, it is important to diagnose, assess prognosis for, and monitor treatment of cancer. Improved, noninvasive diagnostic compositions and

Cyclic dinucleotides for cytokine induction

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FIELD OF THE INVENTION The present invention is in the field of immunotherapy. It concerns cyclic dinucleotides (CDNs) of Formulas I, II and III. In particular, it concerns fluorinated deoxyribo-CDNs and pharmaceutically acceptable salts and prodrugs thereof, which are able to induce production of

Oligonucleotide compositions and their use to induce apoptosis

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FIELD OF THE INVENTION The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis. BACKGROUND OF THE

Oligonucleotide compositions and their use to induce apoptosis

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Пријави се / Пријави се
FIELD OF THE INVENTION The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis. BACKGROUND OF THE

Oligonucleotide compositions and their use to induce apoptosis

Само регистровани корисници могу преводити чланке
Пријави се / Пријави се
FIELD OF THE INVENTION The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis. BACKGROUND OF THE

L-pyranosyl nucleosides

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FIELD OF THE INVENTION This invention relates to L-pyranosyl nucleosides, processes for their preparation, pharmaceutical compositions containing such and methods of using such compounds as anticancer, antiviral, antifungal, antiparasitic and/or antibacterial agents in mammals. BACKGROUND OF THE

L-erythrosyl nucleosides

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FIELD OF THE INVENTION This invention relates to L-erythrosyl nucleosides, processes for their preparation, pharmaceutical compositions containing such and methods of using such compounds as anticancer, antiviral, antifungal, antiparasitic and/or antibacterial agents in meals. BACKGROUND OF THE

6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof

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BACKGROUND OF THE INVENTION The invention relates to 6-purinyl N-(2-chloroethyl) carbamate and thiocarbamate of the general formula I ##STR2## in which X stands for an oxygen or a sulfur atom, and to a process for the preparation thereof. The relevant literature reports certain 6-purinyl derivatives
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