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Страна 1 од 88 резултати
Method for detecting cancer using monoclonal antibodies to new mucin epitopes
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FIELD OF THE INVENTION
This invention relates to hybridoma cell lines that produce new monoclonal antibodies reactive with mucins, particularly to purified mucins, and more particularly to monoclonal antibodies that are capable of preferentially recognizing new epitopes on mucins associated with
Monoclonal antibodies, compositions and methods for detecting mucin-like protein (MLP) as a biomarker for ovarian and pancreatic cancer
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FIELD OF THE INVENTION
The present invention relates to monoclonal antibodies and compositions comprising such antibodies for use in detecting ovarian and pancreatic cancer.
STATEMENT REGARDING SEQUENCE LISTING
The sequence listing associated with this application is provided in text format in lieu
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to anti-pancreatic cancer antibodies and antigen-binding fragments thereof that bind to pancreatic cancer mucin, preferably to a mucin selected from the group consisting of MUC1, MUC5ac and MUC16. More preferably, the
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 2, 2012, is named IMM315US.txt and is 49,649 bytes in size.
BACKGROUND OF THE
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 2, 2012, is named IMM315US.txt and is 49,649 bytes in size.
BACKGROUND OF THE
Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates
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FIELD OF THE INVENTION
The present invention relates to new methods for the production of monoclonal antibodies specific to human cancer-associated antigens and to the hybridomas and monoclonal antibodies produced therefrom. More particularly, the present invention relates to new methods for the
Methods for diagnosis of colon, stomach and pancreatic cancer using antibodies specific for a mucin-type carbohydrate chain
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The present invention relates to a cancer-related pharmaceutical composition containing an antibody capable of recognizing a carbohydrate chain.
It has been reported that when a cell is cancerated, a carbohydrate chain which is not observed in a normal cell, can be detected on the surface of the
Specific mucin expression as a marker for pancreatic cancer
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FIELD OF THE INVENTION
This invention relates to the fields of molecular biology and oncology. Specifically, the invention provides a molecular marker for use in the diagnosis of pancreatic cancer.
BACKGROUND OF THE INVENTION
Several publications are referenced in this application by numerals in
MUCIN 4 expression as a marker for pancreatic cancer
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FIELD OF THE INVENTION
This invention relates to the fields of molecular biology and oncology. Specifically, the invention provides a molecular marker for use in the diagnosis of pancreatic cancer.
BACKGROUND OF THE INVENTION
Several publications are referenced in this application by numerals in
Compounds and methods for selectively targeting tumor-associated mucins
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BACKGROUND OF THE INVENTION
The incidence of breast cancer in the United States in 2010 was 209,060, and the number of deaths was 40,230 (National Cancer Institute U.S. National Institutes of Health). Estrogen receptor negative breast cancer refers to a specific subtype of breast cancer that does
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
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Пријави се / Пријави се
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Mar. 28, 2014, is named IMM343US1_SL.txt and is 56,360 bytes in size.
BACKGROUND OF THE
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
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Пријави се / Пријави се
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Mar. 28, 2014, is named IMM343US1_SL.txt and is 56,360 bytes in size.
BACKGROUND OF THE
Method for discriminating between prostate cancer and a benign prostate disease
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TECHNICAL FIELD
The present invention relates to a method of analyzing diagnostic information pertaining to a benign prostate disease and prostate cancer. The present invention also relates to a method of analyzing diagnostic information based on the blood concentration of mucin-1 having a specific
Polyvalent conjugate vaccine for cancer
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BACKGROUND OF THE INVENTION
Tumor-specific antigens have been identified and pursued as targets for vaccines. Previous work from the inventors' has shown that monovalent vaccines utilizing the tumor antigens Globo H, Lewis.sup.y, GM2, glycosylated MUC-1, Tn(c), sTn(c), or TF(c) conjugated to KLH to
Polyvalent conjugate vaccine for cancer
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Throughout this application, various references are referred to. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains.
BACKGROUND OF THE INVENTION
Tumor-specific
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