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piperidine/гојазност
Веза се чува у привремену меморију
Страна 1 од 61 резултати
Bicyclic piperidine and piperazine derivatives as GPCR modulators for the treatment of obesity, diabetes and other metabolic disorders
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FIELD OF THE INVENTION
The present invention relates to Bicyclic Piperidine and piperazine Derivatives, compositions comprising a Bicyclic Piperidine and piperazine Derivative, and methods of using the Bicyclic Piperidine and piperazine Derivatives for treating or preventing obesity, diabetes, a
Spirosubstituted piperidines as selective melanin concentrating hormone receptor antagonists for the treatment of obesity
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FIELD OF THE INVENTION
This invention relates to antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of metabolic and eating disorders. It generally discloses novel compounds having MCH receptor modulatory activity, pharmaceutical compositions containing one or more
2-substituted benzimidazole piperidines analogs as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
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FIELD OF THE INVENTION
This invention relates to antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of metabolic and eating disorders, novel compounds having MCH receptor modulatory activity, pharmaceutical compositions containing one or more such modulators, methods
Piperidine based MCH antagonists for treatment of obesity and CNS disorders
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FIELD OF THE INVENTION
This invention relates to antagonists of melanin-concentrating hormone (MCH) and their use in the treatment of obesity, eating disorders and diabetes, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds.
BACKGROUND OF THE
Biaryltetrahydroisoquinoline piperidines as selective MCH receptor antagonists for the treatment of obesity and related disorders
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FIELD OF THE INVENTION
This invention relates to antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of metabolic and eating disorders, novel compounds having MCH receptor modulatory activity, pharmaceutical compositions containing one or more such modulators, methods
Piperidine derivative compounds and drugs containing the compounds as the active ingredient
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TECHNICAL FIELD
The present invention relates to a piperidine derivative.
More specifically, the present invention relates to (1) a piperidine derivative of formula (I)
##STR00002## (2) a method for the preparation thereof, (3) a composition comprising it as an active ingredient, (4) a compound of
Piperidine derivatives
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FIELD OF THE INVENTION
This invention relates to new compounds, in particular piperidine derivatives, to processes for preparing such compounds, to their use as inhibitors of acetyl-CoA carboxylase(s), to methods for their therapeutic use, in particular in diseases and conditions mediated by the
Bridged bicyclic piperidine derivatives and methods of use thereof
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FIELD OF THE INVENTION
The present invention relates to Bridged Bicyclic Piperidine Derivatives, compositions comprising a Bridged Bicyclic Piperidine Derivative, and methods of using the Bridged Bicyclic Piperidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a
N-aryl piperidine substituted biphenylcarboxamides
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The present invention is concerned with novel N-aryl piperidine substituted biphenylcarboxamide compounds having apolipoprotein B inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising
Pentadienoyl piperidine derivative and use thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a national phase application under 35 U.S.C. .sctn. 371 of International Application No. PCT/KR2015/009944 filed Sep. 22, 2015, which claims priority to Korean Patent Application No. 10-2014-0126959 filed Sep. 23, 2014. The contents of each
Substituted piperidines as melanocortin receptor agonists
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FIELD OF THE INVENTION
The present invention relates to piperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) agonists. More particularly, the compounds of the present invention are selective agonists of the melanocortin-4 receptor (MC-4R) and are thereby useful for
Substituted piperidines as melanocortin receptor agonists
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SUMMARY OF THE INVENTION
The present invention relates to piperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) agonists. More particularly, the compounds of the present invention are selective agonists of the melanocortin-4 receptor (MC-4R) and are thereby useful
Substituted piperidines and methods of use
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FIELD OF THE INVENTION
The present invention relates generally to the fields of medicinal chemistry and, more specifically, to novel compounds and their use as anti-obesity agents.
BACKGROUND OF THE INVENTION
Obesity, defined as an excess of body fat relative to lean body mass, contributes to and
Piperidine derivatives as melanocortin-4 receptor agonists
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FIELD OF THE INVENTION
The present invention relates to piperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) agonists. More particularly, the compounds of the present invention are selective agonists of the melanocortin-4 receptor (MC-4R) and are thereby useful for
Bridged piperidine derivatives as melanocortin receptor agonists
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FIELD OF THE INVENTION
The present invention relates to bridged piperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) agonists. More particularly, the compounds of the present invention are selective agonists of the melanocortin-4 receptor (MC-4R) and are thereby
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