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Structural classification and properties of ketoacyl reductases, hydroxyacyl dehydratases and enoyl reductases.

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Ketoacyl reductases (KRs), hydroxyacyl dehydratases (HDs) and enoyl reductases (ERs) are part of the fatty acid and polyketide synthesis cycles. Their reverse reactions, catalyzed by acyl dehydrogenases (equivalent to ERs), enoyl hydratases (equivalent to HDs) and hydroxyacyl dehydrogenases

Thyme (Thymus vulgaris L.) leaves and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver.

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The effects of thyme (Thymus vulgaris L.) leaves and its phenolic compounds, thymol and carvacrol, on the activities of xenobiotic-metabolizing enzymes, i.e., phase I enzymes such as 7-ethoxycoumarin O-deethylase (ECOD) and phase II enzymes such as glutathione S-transferase (GST) and quinone

Effects of pharmaceutical formulations containing thyme on carbon tetrachloride-induced liver injury in rats.

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BACKGROUND Herbal supplements are widely used in the treatment of various liver disases, but some of them may also induce liver injuries. Regarding the infuence of thyme and its constituents on the liver, conflicting results have been reported in the literature. The objective of this study was to

Evaluation of cytotoxic, membrane, and DNA damaging effects of Thymus revolutus Célak essential oil on different cancer cells.

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OBJECTIVE In this study, we evaluated Thymus revolutus Célak essential oil and its two main constituents, γ-terpinene and p-cymene, as potential oxidative agents against lung cancer and epidermoid carcinoma cells. METHODS Cell viability assessment was made by CellTiter-Blue1397904493 cell viability

ThYme: a database for thioester-active enzymes.

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The ThYme (Thioester-active enzYme; http://www.enzyme.cbirc.iastate.edu) database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all the enzymes constituting the fatty acid synthesis and polyketide synthesis cycles. These enzymes are active on

Effect of thyme essential oil and selenium on intestine integrity and antioxidant status of broilers.

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1. This study evaluated the duodenal wall integrity, antioxidant status as well as some immunological parameters of broiler chickens supplemented with 0.5 g Thymus vulgaris essential oil (EO)/kg diet and 0.4 mg Se/kg DM (dry matter) derived from sodium selenite. 2. A total of 192 one-d-old randomly

Growth performance and antioxidant enzyme activities in rainbow trout (Oncorhynchus mykiss) juveniles fed diets supplemented with sage, mint and thyme oils.

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This study evaluated effects of dietary supplementation of sage (Salvia officinalis), mint (Mentha spicata) and thyme (Thymus vulgaris) oils on growth performance, lipid peroxidation level (melondialdehyde, MDA) and liver antioxidant enzyme activities (superoxide dismutase, SOD; catalase, CAT;

Influence of broccoli extract and various essential oils on performance and expression of xenobiotic- and antioxidant enzymes in broiler chickens.

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The aim of our present study was to examine the regulation of xenobiotic- and antioxidant enzymes by phytogenic feed additives in the intestine and the liver of broilers. A total of 240 male Ross-308 broiler chickens (1 d old) were fed a commercial starter diet for 2 weeks. On day 15, the birds were

The protection of Thymus vulgaris leaves alcoholic extract against hepatotoxicity of alcohol in rats.

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OBJECTIVE To investigate the protective effect of Thymus vulgaris (T. vulgaris) leaves 70% alcoholic extract against alcohol-mediate hepatotoxicity rats. METHODS The protective effect of T. vulgaris extract was investigated at dose of 500 mg/kg/day (as 0.1 of LD50) orally against alcohol-mediate

Changes of Soil Microbiological Properties during Grass Litter Decomposition in Loess Hilly Region, China.

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Litter, the link between soil and plant, is an important part of nutrient return to soil. Deeply understanding the effect of litter decomposition on soil microbiological properties is important for the sustainable development of grasslands. Three plants (Thymus quinquecostatus Celak., Stipa bungeana

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