9 резултати
OBJECTIVE
To study the chemical constituents from the roots of Buleurum bicaule Helm (Apiaceae).
METHODS
Silica gel, Sephadex LH-20, MPLC Rp-C18 column chromatography, and HPLC were used for isolation of compounds. The structures were elucidated on the basis of 1D- and 2D-NMR technology and
The corticosterone secretion-inducing activities of saikosaponin a, saikosaponin c and saikosaponin d, isolated from the root of Bupleurum falcatum L., and 27 metabolites formed in the murine alimentary tract were studied in mice. Serum corticosterone was determined by high-performance liquid
Five saikosaponins and two saikosapogenins were isolated from the roots of Bupleurum smithii var. parvifolium by column chromatography, preparative-TLC and HPLC, and identified as saikosaponin a, saikosaponin d, saikosaponin b2, saikosaponin b4, chikusaikoside I, saikogenin F and saikogenin G on the
The roots of Bupleurum chinense have a long history in traditional medicine to treat infectious diseases and inflammatory disorders. Two major compounds, saikosaponins A and D, were reported to exert potent anti-inflammatory activity by inhibiting NF-κB. In the present study, we isolated new
Extracts of the root of B. fruticosum L. showed in a biological screening hemolytical activity, hepatoprotective and phagocytosis stimulating effects, and a specific inhibitory activity of leucine aminopeptidase. Further monitoring of the fraction with antihepatotoxic activity led to the isolation