The present invention provides a periodontal composition compounded to include at least one alkaline agent to render a gel or paste having a pH of at least 9.0 to 11.0, and preferably 9.5 to 10.0. The preferred alkaline agent included in the composition is potassium hydroxide, and the composition preferably also includes aluminum hydroxide, calcium carbonate and magnesium carbonate. Of these agents, potassium hydroxide is the most basic compound utilized. Also suitably included in the composition (which can have the consistency of a liquid or suspension, but is preferably compounded as a stable gel or paste) are other excipients including: thickeners that are capable of withstanding the high pH environment without degradation (such as xanthane gum and microcrystalline cellulose); organoleptic agents such as gum arabic and polyethylene glycol; flavorings such as sodium chloride, acesulfame potassium, sodium saccharine, and mint flavorings; stabilizers such as colloidal silica; mild abrasive agents such as microcrystalline formed silica; a foaming agent such as sodium lauryl sulfate or sodium lauryl phosphate; and a fluoride compound such as sodium fluoride or sodium monofluorophosphate for anti-cavity effect.

TAMER International, Ltd.

Periodontal composition

An orally administered composition that includes least one alkaline agent with a pH of at least 9.0 to 12.0, mixed in an aqueous vehicle with relatively high surface tension, high viscosity and lateral adhesion properties. When mixed, a low water soluble emulsion is formed that evenly coats and partially adheres to the lower section of the esophagus and the LES and forms a relatively long acting, protective barrier and partially neutralizes gastric acid. In one embodiment, the alkaline agent is potassium hydroxide and the aqueous vehicle is made of hydroxypropyl methyl cellulose, polyethylene glycol or ethylene glycol and additional thickener agents capable of withstanding high pH environments, such as xanthan gum, croscarmellose sodium, and microcrystalline cellulose. Additional organoleptic agents, such as gum Arabic and polyethylene glycol, flavorings, such as sodium chloride, acesulfame potassium, sodium saccharine, and mint, and stabilizers such as colloidal silica made be added.

senegalia ataxacantha/калијум

Periodontal composition

Method and composition for treating gastro-esophageal disorders

Најкомплетнија база лековитог биља подржана науком