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A neurokinin-1 receptor antagonist reduced hypersalivation and gastric contractility related to emesis in dogs.

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The roles of tachykinin neurokinin-1 (NK1) receptors in the induction of fictive retching, hypersalivation, and gastric responses associated with emesis induced by abdominal vagal stimulation were studied in paralyzed, decerebrated dogs. Vagal stimulation induced gradual increases in salivary

[Transdermal scopolamine reduces nausea, vomiting and sialorrhea in the postoperative period in teeth and mouth surgery].

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Extraoccipital benign childhood partial seizures with ictal vomiting and excellent prognosis.

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In a previous report of 900 patients with epileptic seizures, 24 children had ictal vomiting. Twelve had a previously unrecognised syndrome of early onset benign childhood occipital seizures (EBOS) and three had symptomatic epilepsy. The other nine children with extraoccipital EEG foci or normal EEG

Phenobarbital-responsive ptyalism, dysphagia, and apparent esophageal spasm in a German shepherd puppy.

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A 10-week-old, male German shepherd dog was presented with a primary complaint of episodic ptyalism, dysphagia, vomiting, and mandibular salivary gland enlargement. An esophagram with fluoroscopy showed normal pharyngeal and esophageal function; however, upper gastrointestinal endoscopy and cervical

Ptyalism in pregnancy - a review of epidemiology and practices.

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Ptyalism gravidarum is an oral pathological condition specific to gravidity. We present a review of the literature regarding epidemiology internationally, and then highlight therapies reported by patients and caregivers. This often distressing repeated filling of the mouth with watery saliva in a

A 48-Year-Old Man With Excessive Drooling and Descending Paralysis Requiring Mechanical Ventilation.

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A 48-year-old man presented with a chief report of worsening dysphagia for 5 days. Initially, he had difficulty swallowing solids, but it has progressed to difficulty with liquids. There was associated sialorrhea, hypophonia, slurring of speech, hoarseness of voice, cough, and prominent upper

Evaluation and management of sialorrhea of pregnancy with concomitant hyperemesis.

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This article describes two gravid patients who presented with first-trimester sialorrhea and hyperemesis. Although excessive salivation, especially when accompanied by protracted nausea and vomiting, is an unusual occurrence, it can have serious consequences for both the mother and fetus when left

Acute colonic pseudo-obstruction in a child taking trihexyphenidyl for drooling: Prescribers beware.

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Colonic pseudo-obstruction (Ogilvie's Syndrome) in children is relatively uncommon. We report an unusual case of colonic pseudo-obstruction in an 8-year-old child with cerebral palsy and long-term hypomotility issues being treated for drooling with the anticholinergic medication trihexyphenidyl. He

Treating sialorrhea with transdermal scopolamine. Exploiting a side effect to treat an uncommon symptom in cancer patients.

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BACKGROUND Sialorrhea is a distressing symptom accompanying oral cancer and many heterogeneous cancer-related conditions (chemotherapy-induced nausea, bowel subocclusion, pharmacologic side effects), but its incidence is low in cancer patients. Conversely, it is frequent in patients with

An assay of drug-induced emesis in the squirrel monkey (Saimiri sciureus).

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Emesis has significant evolutionary value as a defense mechanism against ingested toxins; however, it is also one of the most common adverse symptoms associated with both disease and medical treatments of disease. The development of improved antiemetic pharmacotherapies has been

Maropitant administered orally 2-2.5 h prior to morphine and dexmedetomidine reduces the incidence of emesis in cats.

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Objectives The main goal of this study was to test the antiemetic effects of maropitant administered orally 2-2.5 h prior to morphine and dexmedetomidine in cats. Methods Eighty-three healthy female cats were randomized to receive maropitant (8 mg orally; n = 39) or no treatment (control; n = 44),

Assessment of hydromorphone and dexmedetomidine for emesis induction in cats.

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To compare the efficacy of hydromorphone and dexmedetomidine at inducing emesis in cats.Prospective, blinded, randomized crossover study.Veterinary university teaching hospital.12 healthy

Ptyalism gravidarum.

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BACKGROUND Ptyalism gravidarum is of unknown origin and is usually defined as an excessive secretion of saliva, common in women with nausea and vomiting who might have difficulty in swallowing their saliva. METHODS We present here 2 cases complicated by ptyalism gravidarum during all trimesters of

Successful Treatment of Ptyalism Gravidarum With Concomitant Hyperemesis Using Hypnosis.

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Ptyalism gravidarum, or sialorrhea, is the excessive secretion of saliva during pregnancy. Treatment of ptyalism gravidarum is often challenging due to its unknown etiologies. This article discusses a case of ptyalism gravidarum with concomitant hyperemesis in which the condition was successfully

The effects of acupuncture point Pericardium 6 on hydromorphone-induced nausea and vomiting in healthy dogs.

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OBJECTIVE To evaluate the effect of needling at acupuncture point Pericardium 6 on hydromorphone-induced nausea and vomiting. METHODS Randomized controlled clinical study. METHODS Eighty-one mixed-breed, healthy dogs aged 1.8 ± 1.6 years and weighing 14.5 ± 5.6 kg, admitted for elective

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