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Professional and Personal Toxic Exposure in Systemic Sclerosis : Type, Intensity and Probability of Exposition

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Studies show that the risk associated with high cumulative exposure to silica and organic solvents appears to be strongly increased in SSc. Moreover, exposure to silica is associated with a specific type of SSc phenotype with a worse prognosis. However, the type, intensity and probability of these

Blueberries, Bananas, Exercise Recovery

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LAB VISIT #1: ORIENTATION AND BASELINE TESTING (about 1.5 hours): One to two weeks prior to the start of the study, study participants will report to the NCRC Human Performance Lab for orientation and baseline testing. Study participants will be screened to verify "low risk" status for

Impact of Antibiotic Treatment and Extraction on the Oral Micro Biome

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Hypothesis A course of amoxicillin (250 mg ,three times daily for five days), routinely prescribed as a part of treatment protocol for third molar extractions causes a significant shift of the stable oral microbiome . The primary outcome measures are to assess: 1. Relative abundance of different

A Study on Pneumoconiosis Treated With Whole-lung Lavage Combined With Mesenchymal Stem Cells

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Evaluation of SilOss® in Periodontal Surgery

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Study design The study was designed as a split-mouth, double-blind, randomized controlled clinical trial. The purpose of this study is to evaluate the efficacy of a novel synthetic bone regeneration material (Siloss®) in the treatment of periodontal intrabony osseous defects. Ethical clearance has

Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies

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BACKGROUND Pulmonary hypertension is a severe disorder defined by an elevated mean pulmonary arterial pressure (mPAP) as >25 mmHg at rest. A classification of the different types of pulmonary hypertension has been established according to shared pathologic and clinical features as well as similar

Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures 2

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Study rationale: The main risk factors of COPD are tobacco smoking, biomass smoking and occupational factors. Tobacco smoking is well-known risk factor so tobacco induced COPD is completely established. Nevertheless the meaning of occupational factors which are less famous are equally important.

Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures

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IL1-TRAP, Rilonacept, in Systemic Sclerosis

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Overview of Systemic Sclerosis Scleroderma, also known as systemic sclerosis (SSc), is a multisystem disease affecting skin and, more variably, other tissues, commonly including joints, muscles, lungs, the gastrointestinal tract and kidneys. It is one of a group of diseases in which fibrosis is

Plasmonic Photothermal and Stem Cell Therapy of Atherosclerosis Versus Stenting

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Nanoparticles (NPs) are quite safe for an organism but entire kinetics is mostly unknown. The most dangerous approach with lowest level of efficacy and safety is a delivery of NPs with microbubbles. SP+ and mesenchymal SPCs have the similar efficacy as a local delivery system with a lot of

DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)

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It is a sub-study of "DNA-damage biomarkers to monitor and early detect health impairment in workers exposed to Silica (Caesar Stone)" study. Study participants would be recruited during two years of the study. They will be asked to come to a single visit at Pulmonary Laboratory of Tel Aviv Medical

Oxidative Stress Biomarkers to Monitor and Early Detect Health Impairment in Workers Exposed to Silica (Caesar Stone)

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Study participants would be recruited during two years of the study. They will be asked to come to a single visit at Pulmonary Laboratory of Tel Aviv Medical Center. During the meeting, participants will be given a precise explanation about the tests they will perform and after signing the informed

Plasmonic Nanophotothermal Therapy of Atherosclerosis

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Cardiovascular disease (CVD) is one of the main cause of disability and death worldwide. The underlying cause generally is atherosclerosis and more in particular thrombotic rupture of an atherosclerotic plaque in a vital artery. The restoration of blood flow to ischemic myocardium is established as

The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation

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Bovine Colostrum for Patients With Non Alcoholic Fatty Liver Disease

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1. HYPOTHESIS AND STUDY OBJECTIVES 1.1. HYPOTHESIS Ingestion of bovine colostrum powder (BCP) from cows immunized to insulin will improve non alcoholic steatohepatitis and the metabolic syndrome in patients suffering from these conditions 1.2. PRIMARY OBJECTIVES 1.2.1 To determine the efficacy of

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