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N, N-dimethyl-p-toluidine (DMPT; Cas No. 99-97-8), an accelerant for methyl methacrylate monomers in medical devices, is a nasal cavity carcinogen according to a 2-yr cancer study of male and female F344/N rats, with the nasal tumors arising from the transitional cell epithelium. In this study, we
Oral cancer; the sixth most common malignancy in the world has one of the lowest 5 year survival rates. This can be attributed mainly to the delay in diagnosis. The purpose of this study was to evaluate the efficacy of vital staining with toluidine blue dye as an adjunct to standard clinical
OBJECTIVE
To use toluidine blue intra-operatively to identify tumour involved margins after the removal of oral cavity squamous cell carcinoma, and to compare the findings with those of final histopathology.
METHODS
The study was conducted at the Aga Khan University Hospital from December 1, 2009,
When malignant tumours of the oral cavity are of a small size, they are asymptomatic during a long time, and it is difficult to detect them. A method permitting to discover them more easily during the examination would be a precious rescue. In this aim, we have tested the oral coloration with
Toluidine blue staining is not used extensively in the diagnosis of mucosal lesions of the buccal cavity. It is, however, an effective aid, being a diagnostic tool of choice, particularly during screening for neoplastic lesions in populations at risk.
Assesment of recurrences in the oral cavity and pharynx is a serious diagnostic challenge particularly in patient after surgery and irradiation. Observed visible local lesions like oedema, formation of postoperative scars and pain made the diagnostic procedure difficult. Sometimes it's impossible to
Toluidine blue stain is used as a marker to differentiate lesions at high risk of progression in order to improve early diagnosis of oropharyngeal carcinomas. This study focused on 45 oral mucosal lesions in 32 patients (13 female, 19 male). In 9 cases, multiple biopsies were collected. Of the 45
BACKGROUND
The value of chairside adjunctive tests in the detection of oral potentially malignant disorders (OPMDs) remains uncertain.
OBJECTIVE
To determine the effectiveness of toluidine blue in detecting leukoplakia and erythroplakia and its accuracy in identifying cases with oral epithelial
Early detection of oral cancer is of paramount importance in determining the prognosis of oral cancer. Literature suggests that several diagnostic modalities have been proposed to aid a clinician in early detection of oral cancer without much conclusive