[Study on constituents of the aerial parts of Pogostemon cablin].
Nyckelord
Abstrakt
OBJECTIVE
To investigate the chemical constituents of the aerial parts of Pogostemon cablin.
METHODS
The constituents were isolated by column chromatography over silica gel, Sephadex LH-20 and C8. Structures were identified by spectroscopic data analysis.
RESULTS
Thirteen compounds were obtained and elucidated as patchouli alcohol (1), pogostone (2), friedelin (3), epifriedelinol (4), oleanolic acid (5), methyl oleanolate (6), 5alpha-stigmast-3,6-dione (7), stigmast-4-ene-3-one (8), beta-sitosterol (9), pachypodol (10), retusin (11), (-)-guaiacylglycerol (12) and dibutyl phthalate (13).
CONCLUSIONS
Compounds 6, 7, 8, 12 and 13 are isolated from this genus for the first time.