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6 resultat
Toxic-allergic syndrome caused by ingestion of rapeseed oil denatured with aniline.
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In the past four months a new syndrome has caused more than 100 deaths in Spain. The most striking feature is a toxic-allergic pneumonopathy with respiratory distress and radiological evidence of interstitial (occasionally alveolar) exudation. Other features are fever, headache, nausea, muscular and
Acute intoxication with aniline: detection of acetaminophen as aniline metabolite.
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A 47-year-old woman unwittingly ingested an unknown substance together with her breakfast coffee. She suffered effects such as strong headache, generalized cyanosis, and a burning sensation of the lips and collapsed some minutes later. After admission into hospital a methemoglobin level of 35% was
Aniline derivative-induced methemoglobin in rats.
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Methemoglobinemia and hemolysis are the most prominent side-effects of exposure to a wide variety of arylamine drugs, including agricultural and industrial chemicals. Recent studies with aniline and dapsone have identified N-hydroxyl metabolites as the red blood cell (RBC) mediators. This study
Methemoglobinemia resulting from exposure in a confined space: Exothermic self-polymerization of 4,4'-methylene diphenyl diisocyanate (MDI) material.
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A worker attempting to remove solidified material inside a confined space (storage tank) suffered severe methemoglobinemia and almost died. The tank contained liquid 4,4'-methylene diphenyl diisocyanate monomer that had solidified after an equipment power failure caused excessive heating. Wearing a
Applications of organocatalytic asymmetric synthesis to drug prototypes--dual action and selective inhibitors of n-nitric oxide synthase with activity against the 5-HT1D/1B subreceptors.
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The scope of MacMillan's organocatalytic asymmetric conjugate addition reaction of indoles and electron-rich aromatics to α,β-unsaturated aldehydes has been extended to the use of 3-amino crotonaldehydes as substrates. The aromatics used include indoles as well as an aniline and a furan. The scope
A fatal case of chlorate poisoning: confirmation by ion chromatography of body fluids.
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A 49-year-old male chemical industry worker was admitted to intensive care with a 24-hour history of respiratory failure, vomiting, headache, stupor, arterial hypotension, and cyanosed face and limbs. He had acute haemolysis (3.9 g/L plasma haemoglobin concentration) and 30% methaemoglobinaemia.
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