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cholesteatoma/hypoxia
Länken sparas på Urklipp
10 resultat
Expression of hypoxia inducible factor 1 alpha and Von Hippel Lindau protein in human middle ear cholesteatoma.
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OBJECTIVE
To evaluate the role of hypoxia in cholesteatoma progression.
METHODS
Immunohistochemical analysis of paraffin-embedded human specimens.
METHODS
Thirteen middle ear cholesteatomas and 10 samples of normal human external ear canal skin were stained immunohistochemically for the presence of
[Expression of hypoxia-inducible factor-1alpha in middle ear cholesteatoma].
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OBJECTIVE
To explore the pathogenetic mechanism of middle ear cholesteatoma, the aim of this study is to detect the expression of Hypoxia-inducible factor-1alpha in middle ear cholesteatoma and normal external ear canal skin.
METHODS
We used the technology of immunohistochemistry to examine the
Expression of vascular endothelial growth factor in external auditory canal cholesteatoma.
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External ear canal cholesteatoma (EACC) is an invasive and destructive chronic inflammation based on the uncontrolled proliferation of the keratinocytes with an osteolytic character predominantly present in the inferior part of the auditory canal. EACC is a rare otologic entity and the incidence is
Cholesterol and cholesteatoma.
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This is a histological and biochemical study of cholesterol in the middle ear in various chronic otitis media syndromes of 22 cholesteatomatous temporal bones and 52 bioptic specimens. Only three of the temporal bones and 11 surgical specimens showed cholesterol crystals, all of which were in the
Influence of hepatocyte growth factor/scatter factor (HGF/SF) on fibroblast growth factor-2 (FGF-2) levels in external auditory canal cholesteatoma (EACC) cell culture.
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BACKGROUND
In previous studies, we cited circulatory disorders and hypoxia as etiological factors for the formation of external auditory canal cholesteatoma (EACC) resulting in angiogenesis. Here, we investigate how the angiogenic factor hepatocyte growth factor/scatter factor (HGF/SF) influences
[Angiogenic factors in external auditory canal cholesteatoma-fibroblast cell culture].
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BACKGROUND
The external auditory canal cholesteatoma (EACC) is characterized by hyperproliferation of the epithelial and subepithelial tissue. Compared to normal meatal skin, strong expression of FGF-2 and VEGF had previously been detected. Many authors reported that FGF-2 acts via VEGF and is
[Expression and significance of HIF-1alpha and iNOS in human middle ear cholesteatoma epithelium].
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OBJECTIVE
To investigate the expression of Hypoxia inducible factor-1alpha (HIF-1alpha) and inducible Nitric Oxide Synthase (iNOS) in cholesteatoma and approach the possible role of them in the formation and development of the middle ear cholesteatoma.
METHODS
Immunohistochemical SP method was used
Acquired cholesteatoma: summary of the cascade of molecular events.
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BACKGROUND
Cholesteatoma is considered a benign, gradually expanding and destructive epithelial lesion of the temporal bone. The pathogenesis of different classifications of cholesteatoma is marked by similar underlying cellular and molecular processes. Stepwise explanations of the histopathogenesis
Treatable sensorineural hearing loss.
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Sensorineural hearing loss is generally felt to be an untreatable medical condition. However, in some cases, prompt diagnosis and treatment of the underlying condition may reverse the deafness. This article summarizes various treatable forms of sensorineural hearing loss and provides illustrative
[Cochlear implantation at the Ear, Nose and Throat Clinic of the Clinical Center of Vojvodina].
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BACKGROUND
A cochlear implant is a small electronic device that can provide a sense of sound to a person who is profoundly deaf or severely hard-of-hearing. Cochlear implants bypass the damaged hearing systems and directly stimulate the auditory nerve. Signals generated by the implant are sent by
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