Placebo

Pregabalin: On the day of the surgery, 1hour + 15 minutes before the surgery starts, the subject will receive either 300mg of pregabalin or a similarly packaged placebo. On post operative day one, 150 mg of pregabalin or placebo will be given in two doses 12hrs apart.

Pregabalin

Total

Sex: Female, Male

Region of Enrollment

The primary objective of this study is to evaluate the role of three doses of pregabalin on intra and postoperative (48hrs) opioid requirements in patients undergoing fusion of two or more vertebrae.

Postoperative Opioid Requirement

evaluate pain using the visual analog scale (VAS) pain score at two hrs post-op, the morning following surgery 24 hours and 48 hours post-op

Pain Using the Visual Analog Scale (VAS) Pain Score

Find the incidence of 48 hours post operative nausea and vomiting in the target population

Incidence of 48 Hours Post Operative Nausea and Vomiting

48 hours post operative headache, dizziness, sedation and blurred vision

Post Operative Cognitive Function

Measure the level of pre-operative anxiety using the visual analog scale (VAS)

Pre-operative Anxiety

To measure the level of overall anesthesia satisfaction among the two groups at discharge.

Anesthesia Satisfaction

Overall Study

Dr.Singh Nair

Spinal Fusion

On the day of the surgery, 1hour + 15 minutes before the surgery starts, the subject will receive either 300mg of pregabalin or a similarly packaged placebo. On post operative day one, 150 mg of pregabalin or placebo will be given in two doses 12hrs apart.

placebo

Montefiore Medical Center

Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

Double Blinded, Randomized, Placebo Controlled Study in Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

hexanoic acid/back pain

Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

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