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BACKGROUND
Isoeugenol is an important fragrance allergen. The cosmetic industry was recommended voluntarily to reduce concentrations of isoeugenol in finished cosmetic products from 0.2% to 0.02% in 1998. It was suspected that this would reduce the incidence of patch test positivity in individuals
Allergic contact dermatitis is the serious unwanted effect arising from the use of consumer products such as cosmetics. Isoeugenol is a fragrance chemical with spicy, carnation-like scent, is used in many kinds of cosmetics and is a well-known moderate human sensitizer. It was previously reported
The sensitizing properties of the fragrances eugenol and isoeugenol have been investigated experimentally. The potential of these materials to induce sensitization of the respiratory tract was examined using the mouse IgE test, a novel but as yet unvalidated method for the predictive identification
BACKGROUND
In Switzerland, Germany, and Austria, allergic reactions to balsam of Peru (BP) have now made it the third most common contact allergen.
OBJECTIVE
A series of 20 single BP constituents (including resorcinol monobenzoate), established in 1995, was used for patch tests in patients with a
BACKGROUND
To date, only a few cohorts of patients with allergic cheilitis have been described, most of them from Australia and Asia.
OBJECTIVE
To establish the prevalence of cheilitis in a UK specialist contact dermatitis clinic and to identify the most common allergens.
METHODS
We analyzed our
BACKGROUND
Negative patch test results with fragrance allergy markers in the European baseline series do not always predict a negative reaction to individual fragrance substances.
OBJECTIVE
To determine the frequencies of positive test reactions to the 26 fragrance substances for which labelling is
Increasing frequencies of sensitization to the fragrance mix (FM) have been acknowledged as a serious problem for many years. It is well known that the single compounds (SCs) of the FM contribute differently to the FM patch rest reactions. In this study, we were interested in the time trends of the
Because of their widespread use, fragrances are among the most common causes of contact allergic dermatitis, second only to nickel. During a five-year period 3,065 patients with contact dermatitis were patch tested using a specific mix of fragrances. 509 (16.6%) patients were allergic to the
Axillary dermatitis is common and overrepresented in people with contact allergy to fragrances. Many people suspect their deodorants to be the incriminating products. In order to investigate the significance of isoeugenol in deodorants for the development of axillary dermatitis when used by people
The potential of isoeugenol, an important fragrance and flavour ingredient, to induce delayed contact hypersensitivity or to elicit pre-existing sensitization reactions in man was evaluated by analysing patch-test data from dermatitic and non-dermatitic subjects. Results from a total of 6512 patch
Allergic contact dermatitis (ACD) and photo-ACD are cell-mediated delayed hypersensitivity reactions of the skin caused by a wide range of substances. Topical ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), can induce ACD and photo-ACD. Patients with ACD and/or photo-ACD to KP
BACKGROUND
Patch testing to fragrances is an important step in the diagnosis of fragrance allergy.
OBJECTIVE
To determine the usefulness of adding propolis to the European standard series to test for fragrance allergy.
METHODS
A total of 2660 consecutive patients were patch tested with a standard
Eugenol (compound in , 4-allyl-2-methyoxyphenol) and isoeugenol (compound in , 4-propenyl-2-methoxyphenol), both used as a flavor agent in cosmetic and food products, have both prooxidant and antioxidant activities. Their adverse effects such as allergic and inflammatory reaction may be due to their
BACKGROUND
The incidence of allergy induced by fragrances, leading mostly to the development of contact dermatitis and urticaria chronica, has been growing in a large number of countries. In general, allergy is of non-occupational nature, however, it can also have traits of occupational exposure.
BACKGROUND
Isoeugenol, an important fragrance allergen in consumers, has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry. However, no decline in contact allergy to isoeugnol has been detected. It has been speculated that isoeugenol derivatives,