laryngeal neoplasms/feber

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[Reaction of the laryngeal mucosa and skin of the neck to the combined use of irradiation, hyperthermia and chemotherapy in laryngeal cancer].

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Reactions of the laryngeal and neck skin mucosa were studied in 93 laryngeal cancer patients on combined therapy including hyperthermia. Patients in the control groups received no local hyperthermia. Reactions on the laryngeal mucosa (hyperemia, insular and confluent epitheliitis) were observed in

[The treatment of laryngeal cancer by using local hyperthermia].

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Potentiation of the effect of radiation and combined treatment of laryngeal cancer by local hyperthermia was studied in 43 patients. In 51 cases of the control group (radiotherapy), conventionally-dynamic fractionation of dose was used. At 32 Gy, complete or partial regression of tumor was observed

[The effect of local UHF hyperthermia and a fractionated radiation dosage on the incidence of perichondritis during the treatment of laryngeal cancer].

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Perichondritis in patients treated by a continuous course were noted in 12.5 +/- 1.5%, in patients treated by a split method--in 4.6 +/- 1.2%, in chemoradiotherapy--in 5.75 +/- 1.3%, in thermoradiotherapy--in 3.0 +/- 2.9%, and after synchronization using 5-FU and large fractions--in 30.5 +/- 3.9%.

[Radiation therapy with local UHF hyperthermia in the late stages of laryngeal cancer].

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Altogether 47 patients with advanced laryngeal and laryngopharyngeal tumors were treated. Twenty-six patients received multimodality therapy including local UHF-hyperthermia and gamma-beam therapy; 21 patients receiving radiotherapy only were entered in the control group. Hyperthermia was induced by

Comparative results of preoperative chemoradiotherapy and thermochemoradiotherapy for locally advanced laryngeal cancer.

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The study is based on the results of treatment of 60 patients with locally advanced laryngeal cancer (T3-4N0-3M0) exposed to combined treatment: 31 with preoperative chemoradiothera-py, 29 thermochemoradiotherapy. Radiotherapy was performed in the hyperfractionated mode: “1 Gy +1 Gy” (every 4-5

Combined chemoradiotherapy with local microwave hyperthermia for treatment of T3N0 laryngeal carcinoma: a retrospective study with long-term follow-up.

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The purpose of our study was to test the efficacy and toxicity of hyperthermia in conjunction with chemoradiotherapy for T3N0 laryngeal cancer. From 1997-2006, 25 patients diagnosed with T3N0 laryngeal carcinoma who denied laryngectomy were selected for this retrospective study. Patients received a

[Combined radiomodification in the treatment of patients with disseminated laryngeal cancer].

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The paper is devoted to comparative estimation of radiation and combined therapy of laryngeal cancer patients using combined radiomodification including local hyperthermia, total hyperthermia, chemotherapy and a method of dynamic dose fractionation. Complete and significant tumor regression at a

[The study of postoperative infection in patients after laryngeal cancer surgery].

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We evaluated wound infections in major oncological surgery for laryngeal neoplasm and functional neck dissection. Our objective was to determine the incidence and prevalence of infection in a group of laryngectomized patients; we evaluated the temperature, duration of fever, and analytical findings

[Effectiveness of recombinant adenovirus p53 injection on laryngeal cancer: phase I clinical trial and follow up].

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OBJECTIVE To evaluate the efficacy and toxicity of recombinant adenovirus p53 injection (SBN-1) in patients with laryngeal cancer. METHODS Twelve cases with laryngeal cancer, 11 males and 1 female, aged 59.5 +/- 12.4 years, were randomly divided into three groups of 4 patients. The patients received

[Comparative results of conservative chemoradiotherapy and thermochemoradiotherapy for locally advanced laryngeal cancer].

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There were analyzed results of treatment of 58 patients with laryngeal cancer T3-4N0-3M0. Chemoradiotherapy (CRT) was carried out in 27 patients, thermochemoradiotherapy (TCRT)-in 31 patients. Radiotherapy (RT) was performed in hyperfractionated mode (1 Gy + 1 Gy with an interval of 4-5 hours) 5

[The hematopoietic characteristics of laryngeal cancer patients undergoing thermoradiosensitization].

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Peripheral blood and bone marrow were studied in 46 patients suffering laryngeal cancer. Two schedules of radiotherapy with and without local hyperthermia were used. Complex hematologic study included electron microscopy of the bone marrow. Apart from general hematologic parameters, partial erythro-

[Conservative thermochemoradiation therapy of locally advanced laryngeal cancer].

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Thermochemoradiation therapy was performed in 31 patients with laryngeal cancer (T3-4N0-3M0). Radiotherapy was performed in 2 stages 1+1 Gy (every 4-5 hours), 5 times a week to SOD 52-60 Gy with a 2-week break after SOD 30-32 Gy. Local hyperthermia was carried out two times a week before the second

Winner of the "New Investigator Award" at the European Society of Hyperthermia Oncology Meeting 2007. The HYPERcollar: a novel applicator for hyperthermia in the head and neck.

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The purpose of this work was to define all features, and show the potential, of the novel HYPERcollar applicator system for hyperthermia treatments in the head and neck region. The HYPERcollar applicator consists of (1) an antenna ring, (2) a waterbolus system and (3) a positioning system. The

The effect of cisplatin, etoposide and quercetin on Hsp72 expression.

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Heat shock protein 72 (Hsp72) belongs to a group of proteins referred to as molecular chaperones that protect normal and tumour cells against many stressors such as hyperthermia, some commonly used chemotherapeutics and other apoptotic stimuli. Our study was designed to determine whether heat shock

The effect of heat shock, cisplatin, etoposide and quercetin on Hsp27 expression in human normal and tumour cells.

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Heat shock protein 27 (Hsp27) belongs to the group of proteins called molecular chaperones protecting normal and tumour cells against many stressors such as hyperthermia, several commonly used chemotherapeutics as well as other apoptotic stimuli. Our study was designed to determine whether heat

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