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14 resultat
Method and composition to prevent or improve symptoms of musculoskeletal distress degeneration
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FIELD OF THE INVENTION
The present invention relates generally to a composition comprised of ground cartilage and optionally one mineral metal with an acceptable chemical counter-ion to be orally consumed as a method to preventing or improving symptoms of musculoskeletal distress degeneration. More
Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
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TECHNICAL FIELD
The present invention is directed to certain isoxazolone compounds that inhibit the release of inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor (TNF) from cells. The compounds of the invention, therefore, are useful in treating diseases involving unwanted
Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
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TECHNICAL FIELD
The present invention is directed to certain isoxazolone compounds that inhibit the release of inflammatory cytokines such as interleukin-1 (1L-1) and tumor necrosis factor (TNF) from cells. The compounds of the invention, therefore, are useful in treating diseases involving unwanted
Skeletal muscle augmentation utilizing muscle-derived progenitor compositions, and treatments thereof
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FIELD OF THE INVENTION
The present invention relates to muscle-derived progenitor cells (MDCs) and compositions of MDCs and their use in the augmentation of body tissues, particularly skeletal muscle. In particular, the present invention relates to muscle-derived progenitor cells that show long-term
Substituted thiadiazolesulfonamides
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Under the provisions of Section 119 of 35 U.S.C., Applicants hereby claim the benefit of the filing date of German Patent Application Number 19847823.2, filed Oct. 16, 1998, which Application is hereby incorporated by reference.
1. Field of the Invention
The invention relates to novel substituted
Substituted thiadiazolesulfonamides
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Under the provisions of Section 119 of 35 U.S.C., Applicants hereby claim the benefit of the filing date of German Patent Application Number 19847823.2, filed Oct. 16, 1998, which Application is hereby incorporated by reference.
FIELD OF THE INVENTION
The invention relates to novel substituted
Substituted heterocyclic compounds and methods of use
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BACKGROUND OF THE INVENTION
The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the
Substituted heterocyclic compounds and methods of use
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BACKGROUND OF THE INVENTION
The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the
Pyrimidine carboxamides
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FIELD OF THE INVENTION
The present invention relates to novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their
Substituted heterocyclic compounds and methods of use
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BACKGROUND OF THE INVENTION
The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the
Substituted heterocyclic compounds and methods of use
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BACKGROUND OF THE INVENTION
The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the
Substituted heterocyclic compounds and methods of use
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BACKGROUND OF THE INVENTION
The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the
Cannabinoid receptor modulators
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage Application under 35 U.S.C. .sctn.371 of International Application No. PCT/US2010/002360, filed Aug. 27, 2010, which claims priority under 35 U.S.C. .sctn.119(e) to U.S. Provisional Application Nos. 61/275,506, filed Aug.
Cannabinoid receptor modulators
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FIELD OF THE INVENTION
The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB.sub.2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions
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