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Effects of Hormone Replacement Therapy on Cardiovascular Risk and Body Composition Parameters

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Hormone therapy (HT) was available since 1942 in tablets containing conjugated equine estrogens. Since the 1970s, it has been recommended to add progestogens to the treatment of women with a uterus to prevent endometrial hyperplasia. HT has been shown to be very effective in climacteric syndrome,

Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis

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1. Baseline visit prior to initiation of IVF cycle: Review nature of study, confirm surgical diagnosis of endometriosis, obtain informed consent, confirm absence of exclusion criteria 2. Standard IVF and preimplantation genetic screening (prior to study entry): Subjects will undergo standard ovarian

Effect of Progesterone Therapy on Traumatic Subarachinoid Haemorrhage on Clinical Outcome and Resistive Vasculer Indices of Middle Cerebral Artery Transcranial Doppler

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Progesterone is an neurosteroid that can help integrity of blood brain barrier . Traumatic subarachinoid hemorrhage disrupts this blood brain barrier facilitating post traumatic vasospasm and neuronal ischemia. Transcranial doppler can detect cerebral vasoconstriction through resistive vasculer

Menstrual Cycle Characteristics of Healthcare Professionals

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The Covid-19 pandemic has impacted healthcare workers physically and psychologically. Healthcare workers have ben required to work under stressful conditions and take difficult decisions involving ethical implications. Increasing work demands on healthcare professionals conflict with their duties to

Myo-Inositol for Infertility in PCOS

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At the screening visit, blood pressure and heart rate will be measured, weight and height obtained and body mass index calculated (kg/m2). If not already completed at their new patient visit, transvaginal ultrasound will be performed to assess uterine anatomy and obtain antral follicle count, TSH,

Progesterone Levels and Pregnancy Results

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Studies have investigated the relationship between maternal serum progesterone level and low birth weight baby birth, hypertensive disorders of pregnancy, and early pregnancy bleeding. In some cases, patients are supported by oral or vaginal progesterone treatments during pregnancy. We also measure

Darwish Test in Women Using Minipills

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Progestogen-only pills (POP) prevent pregnancy by thickening the mucus in the cervix to stop sperm reaching an egg and assumed to increase Fallopian tubal peristalsis so the fertilized oocyte reaches the endometrial cavity too early for implantation. However, this assumption has no scientific

Pessary Versus Progesterone in Singletons (AP-Singletons)

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This open label, multi-center, randomized controlled trial aims to compare the effectiveness of cervical pessary to vaginal progesterone for prevention of PTB in women with singleton pregnancies and a cervix ≤25 mm. All women at 16 0/7 to 22 0/7 weeks with singleton pregnancies will undergo cervical

Effectiveness of Pretreatment Letrozole Versus Misoprostol Alone in Missed Abortion

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Background and Rationale: Abortion management is one of the most important issues in gyne¬cology. According to the WHO abortion accounts for about 8% of maternal mortality worldwide. The term 'abortion' has become synonymous with induced abortion which is an intentional termination of pregnancy but

Trigger Timing in Ovarian Stimulations

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The objective of this study is to conduct a single center clinical trial, to study whether delay two days of trigger will obtain more good-quality embryos than regular trigger timing in ovarian stimulations by antagonist protocol in in vitro fertilization. Which may further improve culmulative live

Comparison of Myoinositol and Metformin in PCO

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PCOS is a common endocrine disorder in women of reproductive age associated with insulin resistance. Metformin and Myo-inositol being insulin sensitizers improve biochemical parameters. it is aimed to compare the effect of myoinositol and metformin in the resumption of the spontaneous menstrual

Cervical Pessary to Prevent Preterm Singleton Birth in High Risk Population

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Spontaneous preterm birth (sPB) is still a leading cause of neonatal and infant death and responsible of neonatal morbidity as cerebral palsy. In spite of improvements of neonatal care, rates of preterm birth have not changed in the recent 10 years. Clinical risk factors for preterm birth include:

Progesterone in the Treatment of Acute Hemorrhagic Stroke

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The purpose of this clinical trial is to further evaluate the safety and effectiveness of progesterone in the clinical application of major cerebral congestion diseases. The Second Affiliated Hospital of Zhejiang University is the unit in charge of clinical research, and six units participate in the

Ulipristal Acetate in Symptomatic Uterine Fibroid

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There is increasing evidence approving role of medical therapy in treatment of symptomatic uterine fibroid, in the context of women's desire to preserve fertility or not to undergo operation. Among these hormonal therapies, ulipristal acetate (UPA) is an orally administered selective progesterone

Progesterone and Resting Energy Expenditure

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The majority of women report an increase of body weight of about 0.5 kg/year during the menopausal transition. However, the weight gain has not been attributed to menopause itself but rather to, e.g., a decrease of the basal metabolic rate due to aging, less energy expenditure and a non-adapted

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