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valproic acid/kräkning
Länken sparas på Urklipp
Sida 1 från 58 resultat
An adult case of cyclic vomiting syndrome successfully responding to valproic acid.
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Pancreatitis associated with valproic acid therapy.
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Four patients had pancreatitis associated with valproic acid therapy. Three patients received valproic acid at usual doses, and all were free of other symptoms of toxic reactions, with serum levels of valproic acid in the usual therapeutic range. Two patients underwent exploratory laparotomy prior
Reversible Valproic Acid-Induced Parkinsonism and Cognitive Impairment in an Elderly Patient With Bipolar Disorder I.
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Valproic acid (VPA) is approved by the Food and Drug Administration (FDA) for the treatment of manic or mixed episodes associated with bipolar disorder. VPA is also used off-label to treat other conditions in psychiatry such as impulse control disorders, major depression, and posttraumatic stress
Valproic acid in epilepsy: clinical and pharmacological effects.
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The antiepileptic drug valproic acid was studied in an open clinical trial as adjunct medication for 23 patients with uncontrolled seizures of a generalized or partial type. Two-thirds of the patients experienced reduction in seizure frequency ranging from 25 to 100%. Extensive testing revealed no
The adverse effect profile and efficacy of divalproex sodium compared with valproic acid: a pharmacoepidemiology study.
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BACKGROUND
Divalproex sodium has been reported to be better tolerated than valproic acid. To our knowledge, no study has examined whether significant differences in the tolerability and efficacy exist between these preparations in psychiatric patients. The objective of the present study was to
Valproic acid-induced carbamazepine-10,11-epoxide toxicity in children and adolescents.
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The study of 14 children and adolescents shows that the addition of carbamazepine (CBZ) to a basic valproic acid (VPA) therapy can result in unexpectedly high concentrations of carbamazepine-10,11-epoxide (CE) in the serum (up to 13 micrograms/ml). These concentrations were associated with marked
Valproic acid-induced acute pancreatitis and multiorgan failure in a child.
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Valproic acid (VPA) is still an important antiepileptic drug, with the broadest spectrum used in all types of seizures and syndromes. It has serious adverse effects such as hepatotoxicity, hyperammonemic encephalopathy, coagulation disorders, and pancreatitis. The incidence of VPA-associated
Valproic acid poisoning: an evidence-based consensus guideline for out-of-hospital management.
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A review of US poison center data for 2004 showed over 9000 ingestions of valproic acid. A guideline that determines the conditions for emergency department referral and prehospital care could potentially optimize patient outcome, avoid unnecessary emergency department visits, reduce health care
The spectrum of valproic acid-associated pancreatitis.
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OBJECTIVE
Our goal was to characterize valproic acid-associated pancreatitis in children.
METHODS
The charts of all patients with pancreatitis (diagnosed by using strict criteria) associated with valproic acid during a 10-year period were reviewed. Clinical and laboratory results were
Valproic acid hepatic fatalities. III. U.S. experience since 1986.
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We report the results of a third retrospective study of the U.S. experience with fatal hepatotoxicity associated with valproic acid (VPA). In the United States, over one million patients received new prescriptions for VPA during the years 1987 to 1993, and 29 patients developed fatal hepatotoxicity.
Valproic acid-induced hyperammonemia and thrombocytopenia in an elderly woman.
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OBJECTIVE
To describe a case of oral valproic acid-induced hyperammonemia and thrombocytopenia in an elderly patient.
METHODS
A 76-year-old white woman presented to the emergency department with generalized weakness, confusion, nausea, and vomiting. She was taking sodium divalproex 750 mg 3 times
[Hyperammonemia secondary to the use of valproic acid: case report].
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Valproic acid has been widely used for the treatment of epilepsy. Although it is usually well tolerated, it has been associated with some side effects. A poor studied side effect is the hyperammonemia, which independs from the drug hepatotoxic action. The hyperammonemia may occurs just after the
Valproic acid therapy in childhood epilepsy.
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Valproic acid, used alone or in combination with other anticonvulsants in 100 children with epilepsy, improved seizure control in all age groups. Mean improvement in seizure control was 82%. Petit mal seizures responded best, but other types of seizures, even with associated mental and physical
Recurrent pancreatitis induced by valproic acid. A case report and review of the literature.
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Valproic acid represents a new class of anticonvulsants that are widely employed in the management of many types of seizure disorders. Compared with other anticonvulsants, it has been considered relatively free of adverse effects. Recently, acute hepatic failure has been ascribed to valproic acid.
Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy.
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Valproic acid is a widely used drug in the treatment of epilepsy and, compared to other anticonvulsant drugs, is considered safe. The most common side effects of valproic acid ingestion or therapy are transient nausea, vomiting, abdominal cramps, and diarrhea. Most of these complaints are mild.
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