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xerostomia/hypoxia

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The exposition to hypoxia is a stressful stimulus, and the organism develops acclimation mechanisms to ensure homeostasis, but if this fails, it leads to the development of pathological processes. Considering the large number of people under hypoxic conditions, it is of utmost importance to study

Xerostomia Therapy Due to Ionized Radiation Using Preconditioned Bone Marrow-Derived Mesenchymal Stem Cells.

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OBJECTIVES
The aim of this study was to describe the process of regeneration of damaged salivary glands due to ionizing radiations by bone marrow mesenchymal stem cells (BM-MSCs) transplantation that have been given hypoxic preconditioning with 1% O2

[Case of rapid progressive interstitial pneumonia associated with primary Sjogren syndrome].

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A 72-year-old woman with a dry cough and dyspnea on exertion was admitted to our hospital. A chest radiograph showed reticular opacities and volume loss in both lower lung fields. She was troubled with xerostomia and her laboratory test showed positive reaction for anti SS-A and SS-B antibody.

Blood stasis syndrome in Japan and its molecular biological analysis.

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Blood stasis syndrome is one of the pathological concepts of Oriental traditional medicine. In Oriental traditional medicine, blood is thought of as not only blood but also as a living component of the body. In fact, blood stasis syndrome is related to not just circulation disorders but

Amifostine in clinical oncology: current use and future applications.

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Amifostine (Ethyol), an inorganic thiophosphate, is a selective broad-spectrum cytoprotector of normal tissues that provides cytoprotection against ionizing radiation and chemotherapeutic agents, thus preserving the efficacy of radiotherapy and chemotherapy. This review summarizes the preclinical
OBJECTIVE The aim of our study is to investigate the effect of two different methods of continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BIPAP) and oxygen support under spontaneous ventilation on respiration mechanics, gas exchange, dry mouth and face mask lesion

Oral complaints in progressive systemic sclerosis: two cases report.

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Progressive systemic sclerosis is a chronic sclerotic disease which causes diffuse, increased deposition of extracellular matrix in connective tissue with vascular abnormalities, resulting in tissue hypoxia. Aesthetic and facial dysfunction are followed by important oral and facial manifestation of

Comparative study of complete nasal packing with and without airways.

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OBJECTIVE To study and compare the effects of complete nasal packing and nasal packing with airways (uni/bilateral) on blood pressure, arterial oxygen saturation, middle ear pressure, and post-operative subjective complaints. METHODS Ninety patients who underwent bilateral anterior nasal packing for

Poisoning due to tricyclic antidepressant overdosage. Clinical presentation and treatment.

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Tricyclic antidepressants are among the commonest causes of both non-fatal and fatal drug poisoning in the world. Their toxicity is due to effects on the brain, the heart, the respiratory system and the parasympathetic nervous system. Symptoms usually appear within 4 hours of an overdose and all but

[Central anticholinergic syndrome during postoperative period].

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The central anticholinergic syndrome (CAS) includes central signs (somnolence, confusion, amnesia, agitation, hallucinations, dysarthria, ataxia, delirium, stupor, coma) and peripheral signs (dry mouth, dry skin, tachycardia, visual disturbances and difficulty in micturition). It occurs when central

[Acute neurotoxic organophosphate poisoning: insecticides and chemical weapons].

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OBJECTIVE To review clinical and therapeutic bases of an organophosphate poisoning, either with insecticide or nerve agent. METHODS References were obtained from computerized bibliographic research (Medline), from personal data (academic memoir, documents under approbation of the National Defense

An Elderly Man with Fatal Respiratory Failure after Eating a Poisonous Mushroom Podostroma cornu-damae.

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A 73-year-old, previously healthy man presented with nausea, vomiting, diarrhea, dry mouth and febrile sensation 3 hours after eating boiled wild mushrooms. After admission, he showed progressive severe respiratory distress, pancytopenia, azotemia, hypotension, hypoxemia and consolidation of the

[Clinical observation of hypoxic radiotherapy for nasopharyngeal carcinoma].

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OBJECTIVE The clinical application of hypoxic radiotherapy (RT) was developed at a high speed in China in recent years. The protective effect of hypoxic RT on normal tissues has been proved. However, there was not an affirmative answer whether hypoxic RT had any protective effect on tumor. This

[Prophylaxis with antibiotics after radiotherapy in the head and neck area].

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A side effect of radiotherapy in the head and neck area is a reduction of the capillary blood flow and with it, a reduction in local defenses. Depending on the duration and intensity of the radiation, hypoxia, hypocellularity and hypovascularity, may occur, resulting in an increased risk of

Amifostine: the first selective-target and broad-spectrum radioprotector.

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After several decades of preclinical and clinical research, the first approved radioprotective drug, amifostine, is being used in clinical practice. Amifostine has been shown to specifically protect normal tissues from damage caused by radiation and chemotherapy. An inactive prodrug, amifostine is
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