Hydrocolloids as Functional Food Ingredients for Gut Health
Maneno muhimu
Kikemikali
Tarehe
Imethibitishwa Mwisho: | 10/31/2015 |
Iliyowasilishwa Kwanza: | 07/07/2015 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 11/17/2015 |
Iliyotumwa Kwanza: | 11/19/2015 |
Sasisho la Mwisho Liliwasilishwa: | 11/17/2015 |
Sasisho la Mwisho Lilichapishwa: | 11/19/2015 |
Tarehe halisi ya kuanza kwa masomo: | 03/31/2010 |
Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 10/31/2010 |
Tarehe ya Kukamilisha Utafiti: | 11/30/2010 |
Hali au ugonjwa
Uingiliaji / matibabu
Dietary Supplement: Treatment 1
Dietary Supplement: Treatment 2
Dietary Supplement: Treatment 3
Awamu
Vikundi vya Arm
Mkono | Uingiliaji / matibabu |
---|---|
Experimental: Treatment 1 | Dietary Supplement: Treatment 1 Following a 28-day washout one 250ml drink / day containing 8g of agar H1CC2013 as part of normal diet for 28 days |
Experimental: Treatment 2 | Dietary Supplement: Treatment 2 Following a 28-day washout one 250ml drink / day containing 8g of agar H1CC2012 as part of normal diet for 28 days |
Placebo Comparator: Treatment 3 | Dietary Supplement: Treatment 3 Following a 28-day washout one 250ml drink / day containing 8g of maltodextrin as part of normal diet for 28 days |
Vigezo vya Kustahiki
Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
Jinsia Inastahiki Kujifunza | All |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: - Healthy individuals - Age 18-55 years - Non smoking - BMI >20 and <35kg/m2 Exclusion criteria - Smoker - Pregnant and lactating women - Vegetarians and vegans - Lactose intolerant individuals - Diabetes - Cardiovascular disease - Autoimmune/ inflammatory disorders - History of neoplasm - Recent acute illness and/or chronic prescribed or self-prescribed use of anti-inflammatory agents (including aspirin) - Use of broad spectrum antibiotics - Use of drugs active on gastrointestinal motility or laxatives - Use of dietary supplements (specifically probiotics or prebiotics) |
Matokeo
Hatua za Matokeo ya Msingi
1. Change in faecal bacterial composition [up to 28-day treatment period (six/participant in total)]
Hatua za Matokeo ya Sekondari
1. Short chain fatty acid concentrations [up to 28-day treatment period (six/participant in total)]
2. Faecal water barrier function bioactivity [up to 28-day treatment period (six/participant in total)]
3. Bowel habits [7 days following each faecal sample provision (six diaries/participant in total)]
4. Faecal characteristics [up to 28-day treatment period (six/participant in total)]
5. Faecal output weight [up to 28-day treatment period (six/participant in total)]
6. Faecal pH [up to 28-day treatment period (six/participant in total)]
7. Food intake [4 days prior to each faecal sample provision (six diaries/participant in total)]
8. Acute glycaemic response on subset of volunteers (n=20) [Two days (mornings) following crossover intervention study]