Real-time Diagnosis of Pseudopolyps During Colonoscopy
Maneno muhimu
Kikemikali
Maelezo
The colonoscopy with biopsies will be done as standard of care; additional biopsies will be taken for research purposes as detailed above. All of the imaging techniques are part of the accepted standard of care as follows: high definition white light, narrow band imaging, chromoendoscopy, and histologic examination following biopsy. Comparison of the predictive values of the imaging modalities in predicting histology from biopsy underlies the primary question of this research protocol. Cost analysis of modalities versus histology will also be performed. Time for use of the individual modalities will be recorded.
Subjects will be identified by one of the investigators during their outpatient clinic visits or while inpatient at University of Miami Hospital. Subjects who meet the inclusion/exclusion criteria and are scheduled to undergo a colonoscopy for standard of care purposes will be asked to participate in the study. Patients over 18 years of age with a confirmed diagnosis of inflammatory bowel disease with plans for routine colonoscopic evaluation and able to provide informed consent will be included.
Tarehe
Imethibitishwa Mwisho: | 07/31/2018 |
Iliyowasilishwa Kwanza: | 08/10/2011 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 03/15/2012 |
Iliyotumwa Kwanza: | 03/18/2012 |
Sasisho la Mwisho Liliwasilishwa: | 07/31/2018 |
Sasisho la Mwisho Lilichapishwa: | 08/02/2018 |
Tarehe halisi ya kuanza kwa masomo: | 08/31/2011 |
Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 01/31/2013 |
Tarehe ya Kukamilisha Utafiti: | 01/31/2013 |
Hali au ugonjwa
Uingiliaji / matibabu
Other: Patients with pseudopolyps.
Awamu
Vikundi vya Arm
Mkono | Uingiliaji / matibabu |
---|---|
Patients with pseudopolyps. No treatment involved in this study. | Other: Patients with pseudopolyps. All patients will undergo non-invasive endoscopic techniques considered standard of care in surveillance for dysplasia |
Vigezo vya Kustahiki
Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
Jinsia Inastahiki Kujifunza | All |
Njia ya sampuli | Non-Probability Sample |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: - Patients equal to or over 18 years of age with a confirmed diagnosis of inflammatory bowel disease with plans for routine colonoscopic evaluation and able to provide informed consent will be included. Exclusion Criteria: - Patients under 18 years of age. - Patient unwilling or unable to undergo colonoscopy with biopsies or preparation for colonoscopy. |
Matokeo
Hatua za Matokeo ya Msingi
1. Accuracy of non-invasive endoscopic techniques for diagnosis of pseudopolyps as compared to histology as the gold standard for diagnosis [2 years or until 100 patients enrolled, whichever comes first]
Hatua za Matokeo ya Sekondari
1. Cost of non-invasive endoscopic techniques for diagnosis of pseudopolyps as compared to histology as the gold standard for diagnosis [2 years or until 100 patients enrolled, whichever comes first]