Sucralose, Stevia, Gut Microbiome and Glucose Metabolism
Maneno muhimu
Kikemikali
Maelezo
This study will determine the influence of two non-caloric sweeteners on glucose metabolism via the gut microbiome in adult men and women aged 35-55 years.
Tarehe
Imethibitishwa Mwisho: | 02/28/2018 |
Iliyowasilishwa Kwanza: | 06/09/2016 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 06/09/2016 |
Iliyotumwa Kwanza: | 06/14/2016 |
Sasisho la Mwisho Liliwasilishwa: | 03/20/2018 |
Sasisho la Mwisho Lilichapishwa: | 03/21/2018 |
Tarehe halisi ya kuanza kwa masomo: | 01/02/2017 |
Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 01/30/2018 |
Tarehe ya Kukamilisha Utafiti: | 01/30/2018 |
Hali au ugonjwa
Uingiliaji / matibabu
Other: Sucralose
Other: Stevia
Awamu
Vikundi vya Arm
Mkono | Uingiliaji / matibabu |
---|---|
Active Comparator: Sucralose Participants will be asked to consume 180 mg/day of sucralose (in the form of capsules which is equivalent to three 12-oz cans of diet soda) for 14 days. According to the FDA, a 150 lb. person may consume up to 340 mg/day of sucralose (or 5.5 12-oz cans of sucralose-sweetened diet soda). | Other: Sucralose Sweetner |
Active Comparator: Stevia Participants will be asked to consume 180 mg/day of stevia (in the form of capsules which is equivalent to three 12-oz cans of diet soda) for 14 days. According to the FDA, a 150 lb. person may consume up to 800 mg/day of stevia (or about 12 cans of stevia-sweetened diet soda). | Other: Stevia Sweetner |
Vigezo vya Kustahiki
Zama zinazostahiki Kujifunza | 35 Years Kwa 35 Years |
Jinsia Inastahiki Kujifunza | All |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: Generally health adult men and women aged 35-55 years old - Exclusion Criteria:Adults will not be eligible who have chronic disease (cancer, CHD, diabetes, chronic kidney disease); pregnant or breast feeding; menopausal; has a history of bariatric surgery; taking prednisone/steroids, taking medication for PCOS, or take medications that influence blood glucose. - |
Matokeo
Hatua za Matokeo ya Msingi
1. 2-hour glucose [14 days]
Hatua za Matokeo ya Sekondari
1. Gut microbiome [14 days]