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Thulium Contact Laser of Laryngotracheal Stenosis

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliImekamilika
Wadhamini
University Hospital Ostrava

Maneno muhimu

Kikemikali

The purpose of the study is to compare results of the treatment of tumorous and non-tumorous laryngotracheal stenosis using thulium contact laser versus carbon dioxide laser used in the past.

Maelezo

Laryngotracheal stenosis is a serious disease significantly worsening the quality of life. Impaired breathing often leads to tracheotomy, deterioration of the voice leads to communication problems with others and swallowing problems are often present, as well The main causes of laryngotracheal stenosis are post intubation and post tracheostomy conditions, inflammatory process (often autoimmune), tumors (mainly squamous cell carcinoma and chondroma) and trauma. Within the last years there is substantial shift in the treatment strategy from open surgery to endoscopic techniques. However, surgical treatment is often difficult due to demanding exposure of tumor and problematic margins control.

In recent years there has been a development of particular techniques of endoscopic resection of tumors and non-malignant laryngeal glottic and subglottic stenosis using a carbon dioxide (CO2) laser with promising improvement of treatment results.

However, CO2 laser has some limitations, particularly in the treatment of tumors spreading into anterior commissure, because CO2 laser beam cannot get "around the corner". Moreover, subglottic area is also difficult to be reached by CO2 laser beam. Therefore, contact laser with adjustable manipulators with possibility to bend tip of manipulator according to the actual need seems to be of some advantage.

Tarehe

Imethibitishwa Mwisho: 06/30/2019
Iliyowasilishwa Kwanza: 10/22/2015
Uandikishaji uliokadiriwa Uliwasilishwa: 10/24/2015
Iliyotumwa Kwanza: 10/26/2015
Sasisho la Mwisho Liliwasilishwa: 07/30/2019
Sasisho la Mwisho Lilichapishwa: 07/31/2019
Tarehe halisi ya kuanza kwa masomo: 09/30/2015
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 06/30/2018
Tarehe ya Kukamilisha Utafiti: 08/31/2018

Hali au ugonjwa

Laryngeal Carcinoma
Bilateral Vocal Cord Paresis
Subglottic Stenosis

Uingiliaji / matibabu

Procedure: laryngeal carcinoma

Procedure: bilateral vocal cord paralysis

Procedure: subglottic stenosis

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Experimental: laryngeal carcinoma
patients with T1-T2 (some T3) laryngeal carcinoma will undergo treatment using thulium contact laser surgery - tumour resection
Procedure: laryngeal carcinoma
treatment of laryngeal carcinoma using thulium contact laser
Experimental: bilateral vocal cord paralysis
patients with bilateral vocal cord paralysis treated with partial arytenoidectomy will be treated using thulium laser surgery and laterofixation
Procedure: bilateral vocal cord paralysis
treatment of bilateral vocal cord paralysis using thulium contact laser
Experimental: subglottic stenosis
patients with subglottic stenosis treated endoscopically (incisions and dilatation) will be treated with thulium laser surgery
Procedure: subglottic stenosis
treatment of subglottic stenosis using thulium contact laser

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 18 Years Kwa 18 Years
Jinsia Inastahiki KujifunzaAll
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:

1. patients with T1-T2 (some T3) laryngeal carcinoma

2. patients with bilateral vocal cord paralysis treated with partial arytenoidectomy and laterofixation

3. patients with subglottic stenosis treated endoscopically

Exclusion Criteria:

- non signing of informed consent

Matokeo

Hatua za Matokeo ya Msingi

1. Percentage of carcinoma recurrence in the patient population [36 months]

The percentage of carcinoma recurrence will be monitored and evaluated within the study subjects.

Hatua za Matokeo ya Sekondari

1. Percentage of decannulation in the patient population [36 months]

The percentage of decannulation will be monitored among the study subjects.

2. Voice quality (Voice Handicap Index) [36 months]

Voice quality will be assessed according to the Voice Handicap Index, which is an acknowledged measurement tool providing precise evaluation of the condition.

3. Swallowing (SWAL-QOL) questionnaire [36 months]

Swallowing will be assessed in the study group using the SWAL-QOL measurement tool (questionnaire) providing precise evaluation of the condition.

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