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Weight Management in Obese Pregnant Underserved African American Women

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliImekamilika
Wadhamini
Washington University School of Medicine
Washirika
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Maneno muhimu

Kikemikali

This project will test a novel lifestyle intervention to help overweight and obese socioeconomically disadvantaged African American women achieve healthy weight control during and after pregnancy and improve the health of their offspring. The treatment will be given through an existing national home visiting program, Parents As Teachers (PAT), which will facilitate sustainability and nationwide dissemination, if effective. We hypothesize that compared with standard PAT monitoring and counseling (PAT), women randomized to the lifestyle intervention program (PAT+) will have a lower percentage who exceed Institute of Medicine recommendations for gestational weight gain.

Maelezo

Maternal overweight/obesity and inappropriate gestational weight gain increase both maternal and neonatal morbidity and mortality. In addition, offspring of overweight/obese women are at increased risk for neurodevelopmental delay, becoming obese, and developing metabolic diseases. Women who are socioeconomically disadvantaged (SED), especially from African American populations, are particularly susceptible to adverse pregnancy-related outcomes because of their high prevalence rates of obesity. Therefore, successful weight management during pregnancy in SED, African American women has considerable public health implications. We have experience in testing lifestyle interventions among SED nonpregnant women that have been implemented and sustained within community organizations such as Parents As Teachers (PAT), a national home visiting program that provides parent-child education and services free-of-charge to high-needs women, prenatally and post-partum, with up to 25 home visits per year until kindergarten. We propose to conduct a 24-month (6-month prenatal and 18-month post-partum) randomized, controlled trial in overweight and obese SED African American women to evaluate the ability of an innovative lifestyle intervention program (PAT+), delivered by PAT parent educators during prenatal and post-partum home visits, to improve maternal and neonatal/infant weight, metabolic and health outcomes, relative to the standard PAT program (PAT). A programmatic evaluation will determine the applicability of the PAT+ intervention in real world settings by measuring programmatic reach, implementation, acceptability, and sustainability. If effective, PAT+ can be disseminated through this national organization, which currently reaches over 249,000 mothers and 319,000 children participating in 2,173 PAT programs across all 50 states.

Tarehe

Imethibitishwa Mwisho: 01/31/2018
Iliyowasilishwa Kwanza: 01/10/2013
Uandikishaji uliokadiriwa Uliwasilishwa: 01/10/2013
Iliyotumwa Kwanza: 01/14/2013
Sasisho la Mwisho Liliwasilishwa: 01/31/2018
Sasisho la Mwisho Lilichapishwa: 02/04/2018
Tarehe halisi ya kuanza kwa masomo: 09/30/2012
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 04/30/2016
Tarehe ya Kukamilisha Utafiti: 11/30/2017

Hali au ugonjwa

Obesity
Pregnancy
Weight Gain

Uingiliaji / matibabu

Behavioral: Standard Parents as Teachers (PAT)

Behavioral: Parents As Teachers + Lifestyle Int.

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Experimental: Parents As Teachers + Lifestyle Int.
Participants assigned to this group will receive Parents As Teachers Plus (PAT+). This will be a diet and physical activity lifestyle intervention integrated within the standard Parents As Teachers home visiting curriculum. There will be a total of 28 home visits, delivered over 24 months (6 month prenatal phase and 18 month post-partum phase).
Behavioral: Parents As Teachers + Lifestyle Int.
Participants will receive the standard PAT curriculum, plus lifestyle intervention focusing on healthy diet and exercise, through 28 home visits over the course of approximately 2 years.
Active Comparator: Standard Parents as Teachers (PAT)
Participants assigned to this group will receive the standard Parents As Teachers (PAT) home visiting curriculum, focusing on parenting and child development. There will be a total of 28 home visits, delivered over 24 months (6 month prenatal phase and 18 month post-partum phase).
Behavioral: Standard Parents as Teachers (PAT)
Participants will receive visits by Parent Educators, who will deliver the standard PAT curriculum. Participants will receive 28 total visits over the course of approximately 2 years.

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 18 Years Kwa 18 Years
Jinsia Inastahiki KujifunzaFemale
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:

- Pregnant, African American, Socioeconomically disadvantaged

- Established prenatal care at our clinic before 15-6/7 weeks gestation

- Singleton viable pregnancy

- Gestational age 9 to 15 weeks

- Body Mass Index (BMI) of 25-45 kg/m²

Exclusion Criteria:

- Diagnosis of diabetes prior to pregnancy, or test results suggestive of pre-pregnancy diabetes

- Current use of certain medications

- Contraindications to aerobic exercise in pregnancy

- History of contraindicated medical conditions

Matokeo

Hatua za Matokeo ya Msingi

1. Percent of women whose gestational weight gain exceeds Institute of Medicine recommendations [Delivery (when the baby is delivered)]

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