Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty
Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliImekamilika
Wadhamini
Queen's University
Washirika
Pfizer
Glaucoma Research Society of Canada
JARIBIO LA KLINIKI: NCT00485108
BioSeek: nct00485108
Maneno muhimu
Kikemikali
The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT. This study will evaluate the IOP lowering effect of SLT following the topical administration of one of the following: prednisolone 1%, ketorolac 0.5% or artificial tears.
Maelezo
Patients who have been chosen to undergo SLT for glaucoma will be randomized to receive one of prednisolone 1%, ketorolac 0.5% or artificial tears four times a day for 5 days following administration of the laser treatment. The IOP will be measured at various time points following SLT: 1 hour, 2 days, 1 week, 1 month, 3 months, 6 months, and 1 year.
Tarehe
| Imethibitishwa Mwisho: | 08/31/2015 |
| Iliyowasilishwa Kwanza: | 06/08/2007 |
| Uandikishaji uliokadiriwa Uliwasilishwa: | 06/08/2007 |
| Iliyotumwa Kwanza: | 06/11/2007 |
| Sasisho la Mwisho Liliwasilishwa: | 09/20/2015 |
| Sasisho la Mwisho Lilichapishwa: | 09/22/2015 |
| Tarehe halisi ya kuanza kwa masomo: | 12/31/2006 |
| Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 05/31/2009 |
| Tarehe ya Kukamilisha Utafiti: | 11/30/2014 |
Hali au ugonjwa
Primary Open Angle Glaucoma
Pseudoexfoliation Glaucoma
Uingiliaji / matibabu
Drug: 1
Drug: 2
Drug: 3
Awamu
-
Vikundi vya Arm
| Mkono | Uingiliaji / matibabu |
|---|---|
| Active Comparator: 1 Prednisolone 1% eye drop | Drug: 1 eye drop once in each eye treated, 4 times / day for 5 days post-laser |
| Active Comparator: 2 ketorolac 0.5% eye drop | Drug: 2 eye drop once in each eye treated, 4 times / day for 5 days post-laser |
| Placebo Comparator: 3 Artificial Tears (methyl cellulose eye drop) | Drug: 3 eye drop once in each eye treated, 4 times / day for 5 days post-laser |
Vigezo vya Kustahiki
| Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
| Jinsia Inastahiki Kujifunza | All |
| Hupokea Wajitolea wa Afya | Ndio |
| Vigezo | Inclusion Criteria: - primary open angle glaucoma, pseudo exfoliation glaucoma Exclusion Criteria: - previous incisional glaucoma surgery |
Matokeo
Hatua za Matokeo ya Msingi
1. Intraocular pressure lowering effect [1 hour, 2 days, 1 month, 3 months, 6 months and 1 year]
Hatua za Matokeo ya Sekondari
1. intraocular pressure elevation [1 hour, 2 days, 1 month]
