Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical Trial
Maneno muhimu
Kikemikali
Maelezo
Context: Research on natural products with therapeutic, analgesic or antimicrobial purpose should be encouraged to create new drugs. Acmella oleracea, typical plant of the Northern region of the country and popularly known as jambu, has aroused the interest of researchers because of its therapeutic potential. Objective: To evaluate the potential topical analgesic and antimicrobial of Acmella oleracea plant extract from the skin antisepsis in venipuncture procedures. Methods: This is a clinical, randomized, controlled trial with healthy volunteers recruited at the Clinic I of the collection of biological materials sector of the Hospital das Clinicas Samuel Libânio, in Pouso Alegre-MG. The plant extract A. oleracea manipulated with Transcutol® and 70% alcohol were used in the volunteers before the venipuncture procedure as allocation in study groups. Held collection of skin microbiota by the swab technique and the end of the venipuncture procedure was applied to the volunteer, the visual numeric scale (VNS) standard to determine the degree of pain.
Tarehe
| Imethibitishwa Mwisho: | 05/31/2016 |
| Iliyowasilishwa Kwanza: | 05/22/2016 |
| Uandikishaji uliokadiriwa Uliwasilishwa: | 06/06/2016 |
| Iliyotumwa Kwanza: | 06/07/2016 |
| Sasisho la Mwisho Liliwasilishwa: | 06/06/2016 |
| Sasisho la Mwisho Lilichapishwa: | 06/07/2016 |
| Tarehe halisi ya kuanza kwa masomo: | 08/31/2015 |
| Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 08/31/2015 |
| Tarehe ya Kukamilisha Utafiti: | 08/31/2015 |
Hali au ugonjwa
Uingiliaji / matibabu
Other: Acmella oleracea
Other: alcohol 70%
Awamu
Vikundi vya Arm
| Mkono | Uingiliaji / matibabu |
|---|---|
| Active Comparator: Acmella oleracea The plant extract A. oleracea manipulated with Transcutol® were used in the volunteers 3 minutes before the venipuncture | Other: Acmella oleracea The plant extract A. oleracea manipulated with Transcutol® were used in the volunteers before the venipuncture procedure as allocation in study groups. Held collection of skin microbiota by the swab technique and the end of the venipuncture procedure was applied to the volunteer, the visual numeric scale (VNS) standard to determine the degree of pain. |
| Placebo Comparator: alcohol 70% 70% alcohol were used in the volunteers 3 minutes before the venipuncture | Other: alcohol 70% 70% alcohol were used in the volunteers before the venipuncture procedure as allocation in study groups. Held collection of skin microbiota by the swab technique and the end of the venipuncture procedure was applied to the volunteer, the visual numeric scale (VNS) standard to determine the degree of pain. |
Vigezo vya Kustahiki
| Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
| Jinsia Inastahiki Kujifunza | All |
| Hupokea Wajitolea wa Afya | Ndio |
| Vigezo | Inclusion Criteria: - healthy volunteers - without restriction as to ethnicity - educational level and social class who agreed to participate by signing the Informed Consent and Informed (IC ) Exclusion Criteria: - pregnant women (due to contractile properties that can cause ) - cancer patients - chronic and refusal to participate in the study kidney |
Matokeo
Hatua za Matokeo ya Msingi
1. The degree of pain in 15 healthy volunteers will be measured by the visual numeric scale (VNS) standard immediately after the venipuncture procedure. [1 day]
2. The skin microflora in 15 healthy volunteers will be measured counted the microorganism isolated by swab technique and plated on plates containing the medium Standard Methods Agar (PCA). [1 day]
