Swahili
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)

Body Composition and White Adipose Tissue Inflammation

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliKuajiri
Wadhamini
Memorial Sloan Kettering Cancer Center
Washirika
Weill Medical College of Cornell University

Maneno muhimu

Kikemikali

The investigators want to find a better way to predict the risk of having fatty tissue inflammation by using a different approach to finding out body fat composition. In this study, the investigators want to estimate the body fat composition using a DEXA scan. DEXA stands for dual energy X-ray absorptiometry. It is the standard and established test to determine bone mineral density (how strong the bones are) to diagnose osteoporosis. This test can also be used to determine the body composition including percent body fat and lean mass. The investigators will compare the participants DEXA scan results for body fat composition to the inflammation found in the breast tissue from the mastectomy to see if there is a relationship. If successful, this may help us predict which patients may be at risk for breast cancer in the future. In addition, the investigators will compare the participants DEXA scan results for body fat composition and inflammation found in the fat tissue from the mastectomy or prostatectomy to the level of exercise activity as measured by a short questionnaire to see if there is a relationship. The investigators will also measure the participants waist to hip ratio.
Finally, at the time the participant has blood drawn for their standard presurgical testing, the investigators will also test the blood for prediabetes using a blood test called hemoglocin A1c. The investigators will also measure for the participants waist to hip ratio, and a Hgb A1c blood drawn will be take at the time of presurgical testing. If not feasible, Hgb A1c can be drawn at a separate visit prior to the DEXA scan. If successful, this may help us predict which patients may be at risk for breast cancer in the future.

Tarehe

Imethibitishwa Mwisho: 03/31/2020
Iliyowasilishwa Kwanza: 03/10/2016
Uandikishaji uliokadiriwa Uliwasilishwa: 03/14/2016
Iliyotumwa Kwanza: 03/17/2016
Sasisho la Mwisho Liliwasilishwa: 04/06/2020
Sasisho la Mwisho Lilichapishwa: 04/07/2020
Tarehe halisi ya kuanza kwa masomo: 11/03/2015
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 10/31/2021
Tarehe ya Kukamilisha Utafiti: 10/31/2021

Hali au ugonjwa

Breast Cancer
Prostate Cancer
Body Composition
White Adipose Tissue Inflammation

Uingiliaji / matibabu

Device: DEXA Scan

Behavioral: Godin Leisure Time Exercise Questionnaire (GLTEQ)

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Breast Cancer
DEXA scan will be carried out 1 to 30 days prior to mastectomy. Patients will also complete the Godin Leisure Time Exercise Questionnaire (GLTEQ) and their waist to hip ratio will be measured.
Prostate Cancer
DEXA scan will be carried out 1 to 30 days prior to radical prostatectomy. Patients will also complete the Godin Leisure Time Exercise Questionnaire (GLTEQ) and their waist to hip ratio will be measured.

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 18 Years Kwa 18 Years
Jinsia Inastahiki KujifunzaAll
Njia ya sampuliNon-Probability Sample
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:

- Age ≥ 18

- Female

- All BMIs

- Patients undergoing mastectomy at MSKCC (i.e. Nipple-sparing mastectomy, skin-sparing mastectomy, simple mastectomy, modified radical mastectomy, radical mastectomy); mastectomy may be either prophylactic or therapeutic. OR

- Patients undergoing hysterectomy at MSKCC

- History of prior breast surgeries/procedures is acceptable

Exclusion Criteria:

- Pregnancy (confirmed or suspected);

- Inability to lay supine on equipment table and maintain the position for the necessary time;

- Weight superior to the maximum allowed by the DEXA machine (over 350 lbs or 158 kg);

- Greater than 10% baseline weight loss in the past year;

- Planned surgical procedure is not a Mastectomy (i.e. breast conservation surgery or other non-mastectomy procedure; such as lumpectomy) or hysterectomy

- Metastatic cancer

- History of Wasting Syndromes or Cachexia

- Use of daily NSAIDs, aspirin, or steroids (other than inhaled or topical) within 30 days of surgery

- Use of neoadjuvant systemic or radiation therapy.

Matokeo

Hatua za Matokeo ya Msingi

1. fat percentage [1 year]

as measured by DEXA

2. presence of White Adipose Tissue Inflammation (WATi ) [1 year]

as measured by DEXA

Jiunge na ukurasa
wetu wa facebook

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi

  • Inafanya kazi katika lugha 55
  • Uponyaji wa mitishamba unaungwa mkono na sayansi
  • Kutambua mimea kwa picha
  • Ramani ya GPS inayoshirikiana
  • Soma machapisho ya kisayansi yanayohusiana na utafutaji wako
  • Tafuta mimea ya dawa na athari zao
  • Panga maslahi yako na fanya tarehe ya utafiti wa habari, majaribio ya kliniki na ruhusu

Andika dalili au ugonjwa na usome juu ya mimea ambayo inaweza kusaidia, chapa mimea na uone magonjwa na dalili ambazo hutumiwa dhidi yake.
* Habari zote zinategemea utafiti wa kisayansi uliochapishwa

Google Play badgeApp Store badge