Common Bile Duct Pressures in Patients With and Without Cholelithiasis
Maneno muhimu
Kikemikali
Maelezo
A prospective study of cases and controls was designed using a previously validated model for the study of occult pancreatobiliary reflux in patients undergoing gastrectomy for gastric cancer, in which cholecystectomy is routine according to the oncological surgery protocol for gastric cancer of our institution. The study universe was constituted by a convenience sample in which all patients undergoing gastrectomy for gastric cancer during the period between January 2015 and June 2017 the investigators included. All patients included in this study signed a detailed informed consent regarding the interventions to be performed and the objectives of the study.
Cholecystectomy was performed in all patients after the section of the duodenum. Before the manipulation and dissection of the Calot triangle, a sample of 5 to 10 cc of bile was taken directly from the gallbladder. The sample was stored in a sterile tube at room temperature and immediately sent for processing. The technicians of our institutional laboratory that processed the sample did not know the details of the study. The cholecystectomy was then carried out until the cystic was reached and was cut as proximally as possible to the gallbladder. Through the cystic duct, a 4 French feeding tube equivalent to 1.35 mm in diameter (Well Lead®, Hamburg, Germany) was introduced until reaching a distance of 3 cm distal to the junction of the cystic duct and the common bile duct. Once tested for patency, this probe was connected to a standard pressure transducer used to measure intra-arterial pressure (Edwards Lifesciences™, Irvine, California, USA) and this was connected to a B40 monitor (General Electric® Medical Systems, Milwaukee, WI, USA) with the ability, among other functions, to perform pressure measurements in millimeters of mercury. The level of the junction of the cystic duct and the common bile duct was taken as a zero point, as previously described. Once the whole system was irrigated with 0.9% physiological solution and the zero point was established on the monitor with the system closed, the system was opened and pressures were measured. The minimum, maximum and mean pressures were recorded for one minute. After the procedure was completed, the gastrectomy was performed.
Tarehe
Imethibitishwa Mwisho: | 06/30/2019 |
Iliyowasilishwa Kwanza: | 07/16/2019 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 07/17/2019 |
Iliyotumwa Kwanza: | 07/18/2019 |
Sasisho la Mwisho Liliwasilishwa: | 07/17/2019 |
Sasisho la Mwisho Lilichapishwa: | 07/21/2019 |
Tarehe halisi ya kuanza kwa masomo: | 12/31/2014 |
Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 06/29/2017 |
Tarehe ya Kukamilisha Utafiti: | 07/09/2019 |
Hali au ugonjwa
Uingiliaji / matibabu
Diagnostic Test: MEASUREMENT OF COMMON BILE DUCT PRESSURES
Awamu
Vikundi vya Arm
Mkono | Uingiliaji / matibabu |
---|---|
PATIENTS WITH CHOLELITHIASIS COMMON BILE DUCT PRESSURES WERE MEASURED IN PATIENTS WITH CHOLELITHIASIS | |
PATIENTS WITHOUT CHOLELITHIASIS COMMON BILE DUCT PRESSURES WERE MEASURED IN PATIENTS WITHOUT CHOLELITHIASIS |
Vigezo vya Kustahiki
Jinsia Inastahiki Kujifunza | All |
Njia ya sampuli | Non-Probability Sample |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: - All patients with normal values of amylase, lipase, and liver function tests measured 24 hours before the intervention Exclusion Criteria: - Patients previously cholecystectomized - Patients with clinical, radiological and laboratory evidence of common bile duct stones |
Matokeo
Hatua za Matokeo ya Msingi
1. Common bile duct pressures [Two and a half years]
Hatua za Matokeo ya Sekondari
1. Levels of amylase and lipase in bile [Two and a half years]