Diode Laser Study for Periodontal Maintenance Patients

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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HaliImekamilika

Wadhamini

University of Nebraska

JARIBIO LA KLINIKI: NCT01215201

BioSeek: nct01215201

Maneno muhimu

Kikemikali

This study tries to determine whether the additional use of laser with "cleaning" (known as scaling and root planning) will result in the reduction of inflammation, reduction of bleeding upon examination and reduction of pocket depth in patients who are being maintained on a regular basis but have pocket depths that are ≥5mm with bleeding. When a pocket is bleeding, it is inflamed. It is usually "cleaned" with periodontal instruments (root-planed) to establish health. Some research also advocates using laser therapy to treat a bleeding pocket. Laser therapy is presently being performed in some dental offices and dental colleges. This research is trying to see if the additional laser therapy is beneficial.

Maelezo

The purpose of this study is to determine whether the adjunctive use of diode laser with scaling and root planing is more effective than scaling and root planing alone in clinically reducing periodontal pocket depth (PD), reducing bleeding on probing (BOP) and gaining of clinical attachment level (CAL). It also assesses whether diode laser with scaling and root planing will have an effect on cytokines and inflammatory biomarkers compared to root planing alone.

Any adult who is currently a routine periodontal maintenance patient and has one or more ≥ 5mm pockets with BOP will be invited to participate in the study. If they choose to participate, they will sign an informed consent. Crevicular fluid samples from each test site and another non-involved site in the mouth will be collected utilizing the standard protocol and frozen for later analyses of the presence of certain inflammatory biomarkers (IL-1β). Baseline data (i.e., PD, CAL, BOP, suppuration, supragingival plaque, subgingival restorative margins, smoking status) will be collected. The involved teeth will then be randomly treated with scaling and root-planing with hand instruments and diode laser (test) or scaling and root-planing with hand instruments alone. The patient will return 3 months later for follow-up data collection. He/she will then receive his/her regular 3 month maintenance therapy.

The changes between baseline and 3 months for the clinical parameters and gingival crevicular fluids' inflammatory biomarkers will be compared between test and control experimental sites.

Tarehe

Imethibitishwa Mwisho:	09/30/2018
Iliyowasilishwa Kwanza:	10/03/2010
Uandikishaji uliokadiriwa Uliwasilishwa:	10/03/2010
Iliyotumwa Kwanza:	10/05/2010
Sasisho la Mwisho Liliwasilishwa:	10/29/2018
Sasisho la Mwisho Lilichapishwa:	10/31/2018
Tarehe halisi ya kuanza kwa masomo:	04/30/2010
Tarehe ya Kukamilisha Msingi iliyokadiriwa:	05/31/2011
Tarehe ya Kukamilisha Utafiti:	06/30/2011

Hali au ugonjwa

Periodontal Diseases

Periodontitis, Apical, Chronic Nonsuppurative

Suppuration of Gingival Crevice

Uingiliaji / matibabu

Procedure: Scaling and Root Planing Alone

Procedure: Diode Laser plus Scaling and Root Planing

Awamu

Vikundi vya Arm

Mkono	Uingiliaji / matibabu
Other: Scaling and Root Planing Alone Control group	Procedure: Scaling and Root Planing Alone Use periodontal hand instruments (curettes) to remove plaque, bacteria, and deposits on the root's surfaces.
Experimental: Diode Laser plus Scaling and Root Planing Diode Laser is used in addition to Scaling and root planing procedure.	Procedure: Diode Laser plus Scaling and Root Planing First: Periodontal hand instruments (curettes) were used to remove plaque, bacteria, and deposits on the root's surfaces (within a periodontal pocket) Then: Biolase 940 nm Ezlase diode laser was used to sterilize a periodontal pocket. Power: 0.80 Watts Wavelength: 940 nm Energy level: 0.80 Joules/second Mode of beam delivery: continuous

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza	30 Years Kwa 30 Years
Jinsia Inastahiki Kujifunza	All
Hupokea Wajitolea wa Afya	Ndio
Vigezo	Inclusion Criteria: - Any adult periodontal maintenance patient having had chronic periodontitis with last active therapy at least 3 months prior and with 1 or more sites/subject with ≥5mm probing depth that have bleeding on probing and/or suppuration. They have signed an informed consent form to participate in the study. Exclusion Criteria: - Subjects who are un-controlled diabetics, use NSAIDS regularly for chronic disease/pain, used antibiotics for the last 3 months, require antibiotic coverage for therapy, are pregnant and below age 30.

Matokeo

Hatua za Matokeo ya Msingi

1. Periodontal clinical parameters [3 months]

Reduction in Probing Depth, Gaining of clinical attachment level, Reduction of Bleeding upon Probing, Reduction of Plaque accumulation, reduction of IL-1B inflammatory marker.