Encapsulated Juice Powder Concentrate for Preventing Common Cold Symptoms
Maneno muhimu
Kikemikali
Maelezo
Common cold is the most frequent acute illness in industrialised societies. Though it is usually benign, it is a leading cause of absence from work and doctor visits, causing an enormous economic burden including lost productivity and treatment costs.
Common cold is caused by a variety of viruses, with rhinoviruses and corona viruses as the most common. There is currently no treatment for common cold, thus therapy is focussed on symptom relief only. Prevention strategies for common cold include lifestyle measures such as avoiding infected people and regular hand washing during cold season. Dietary supplements including herbs and vitamins have been suggested as preventive strategies for common cold.
Juice Plus+® is a dietary supplement composed primarily of juice powder concentrate and pulp from fruits and vegetables. It contains several antioxidants including vitamin C, vitamin E, beta-carotene and folate. One randomized study reported reduction in work days lost to illness in the Juice Plus+® group compared to the placebo group. However, the clinical benefit for preventing common cold symptoms has not yet been tested in a large adult population.
Tarehe
| Imethibitishwa Mwisho: | 08/31/2010 |
| Iliyowasilishwa Kwanza: | 10/20/2008 |
| Uandikishaji uliokadiriwa Uliwasilishwa: | 10/20/2008 |
| Iliyotumwa Kwanza: | 10/22/2008 |
| Sasisho la Mwisho Liliwasilishwa: | 09/08/2010 |
| Sasisho la Mwisho Lilichapishwa: | 10/04/2010 |
| Tarehe ya matokeo ya kwanza yaliyowasilishwa: | 09/08/2010 |
| Tarehe ya matokeo ya kwanza ya QC yaliyowasilishwa: | 09/08/2010 |
| Tarehe ya matokeo ya kwanza kuchapishwa: | 10/04/2010 |
| Tarehe halisi ya kuanza kwa masomo: | 08/31/2008 |
| Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 06/30/2009 |
| Tarehe ya Kukamilisha Utafiti: | 06/30/2009 |
Hali au ugonjwa
Uingiliaji / matibabu
Dietary Supplement: Juice Plus
Dietary Supplement: Placebo
Awamu
Vikundi vya Arm
| Mkono | Uingiliaji / matibabu |
|---|---|
| Experimental: Juice Plus | Dietary Supplement: Juice Plus Juice Plus+® is a dietary supplement from concentrated fruits (apple, orange, pineapple,cranberry, cherry (acerola), papaya and peach) and vegetables (carrot, parsley, beet, broccoli, kale, cabbage, spinach, and tomato).
Subjects will take four capsules of Juice Plus+® daily. |
| Placebo Comparator: Placebo | Dietary Supplement: Placebo Four capsules of placebo daily. |
Vigezo vya Kustahiki
| Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
| Jinsia Inastahiki Kujifunza | All |
| Hupokea Wajitolea wa Afya | Ndio |
| Vigezo | Inclusion Criteria: - Female or male, 18-65 years of age. - Able and willing to take the active or placebo capsules over the whole study period. - Health care professionals with essential patient contact (physicians, nurses, physiotherapists, etc) in Berlin, Germany. - Written informed consent. Exclusion Criteria: - Known or suspected hypersensitivity or allergy to one of the ingredients of Juice Plus+®. - Refusal to stop intake of additional vitamin supplements during study. - Pregnancy or Lactation. - Alcohol addiction, drug abuse or any other condition considered by the investigator to interfere with study procedures. - Language limitations regarding interviews and questionnaires. |
Matokeo
Hatua za Matokeo ya Msingi
1. Number of Days With at Least Moderate (i.e. Moderate or Severe) Common Cold Symptoms. [within 6 months (after 2 months run-in period)]
Hatua za Matokeo ya Sekondari
1. Secondary Endpoints of This Study Are Mean Health-related Quality of Life, Mean Common Cold Related Total Costs, Direct and Indirect (Productivity Loss) Costs [Baseline, months 2,4,6,8.]
