Exercise Training in Obesity-prone Black and White Women
Maneno muhimu
Kikemikali
Maelezo
Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.
Time of initial weight loss was defined as the time needed to reach the goal of 25 kg/m2 BMI. The women will then be evaluated one year after this time and the amount of weight gain will be determined.
Tarehe
| Imethibitishwa Mwisho: | 09/30/2017 |
| Iliyowasilishwa Kwanza: | 08/28/2003 |
| Uandikishaji uliokadiriwa Uliwasilishwa: | 08/28/2003 |
| Iliyotumwa Kwanza: | 08/31/2003 |
| Sasisho la Mwisho Liliwasilishwa: | 11/15/2017 |
| Sasisho la Mwisho Lilichapishwa: | 11/19/2017 |
| Tarehe halisi ya kuanza kwa masomo: | 11/30/2000 |
| Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 11/30/2007 |
| Tarehe ya Kukamilisha Utafiti: | 11/30/2007 |
Hali au ugonjwa
Uingiliaji / matibabu
Behavioral: Diet
Behavioral: Diet plus aerobic exercise
Behavioral: Diet plus resistance exercise
Awamu
Vikundi vya Arm
| Mkono | Uingiliaji / matibabu |
|---|---|
| Active Comparator: Diet only | |
| Experimental: Diet plus aerobic exercise | Behavioral: Diet plus aerobic exercise |
| Experimental: Diet plus resistance exercise | Behavioral: Diet plus resistance exercise |
Vigezo vya Kustahiki
| Zama zinazostahiki Kujifunza | 21 Years Kwa 21 Years |
| Jinsia Inastahiki Kujifunza | Female |
| Hupokea Wajitolea wa Afya | Ndio |
| Vigezo | - Normoglycemic - BMI between 27-30 - Non smoker - Premenopausal - Physically untrained - Family history of obesity |
Matokeo
Hatua za Matokeo ya Msingi
1. Weight loss [6 months]
2. Change in weight after initial weight loss [12 months after initial weight loss (maximum 18 months after randomization)]
Hatua za Matokeo ya Sekondari
1. Insulin sensitivity [6 months post baseline]
2. Insulin sensitivity [18 months post baseline]
3. Change in visceral fat [6 months post baseline]
4. Change in visceral fat [18 months post baseline]
5. Change in cholesterol [6 months post baseline]
6. Change in cholesterol [18 months post baseline]
7. Change in triglycerides [6 months post baseline]
8. Change in triglycerides [18 months post baseline]
9. Change in resting energy expenditure [6 months post baseline]
10. Change in resting energy expenditure [18 months post baseline]
