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Korean Red Ginseng and Metabolic Syndrome

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliImekamilika
Wadhamini
The Korean Society of Ginseng

Maneno muhimu

Kikemikali

Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not metabolic syndrome.
The investigators hypothesize that Korean red ginseng could improve each constituents of metabolic syndrome, arterial stiffness, and inflammatory markers.
The aim of this study is to determine effects of Korean red ginseng on cardiovascular risks in subjects with metabolic syndrome.

Maelezo

The details of study objective are followed by these:

- comparison of blood pressure before and after Korean red ginseng administration

- comparison of metabolic indicator before and after Korean red ginseng administration

- comparison of oxidative stress and inflammatory markers before and after Korean red ginseng administration

- comparison of arterial stiffness before and after Korean red ginseng administration

Tarehe

Imethibitishwa Mwisho: 01/31/2012
Iliyowasilishwa Kwanza: 09/10/2009
Uandikishaji uliokadiriwa Uliwasilishwa: 09/10/2009
Iliyotumwa Kwanza: 09/13/2009
Sasisho la Mwisho Liliwasilishwa: 02/22/2012
Sasisho la Mwisho Lilichapishwa: 02/26/2012
Tarehe ya matokeo ya kwanza yaliyowasilishwa: 01/18/2012
Tarehe ya matokeo ya kwanza ya QC yaliyowasilishwa: 01/18/2012
Tarehe ya matokeo ya kwanza kuchapishwa: 02/23/2012
Tarehe halisi ya kuanza kwa masomo: 07/31/2009
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 12/31/2010
Tarehe ya Kukamilisha Utafiti: 12/31/2010

Hali au ugonjwa

Metabolic Syndrome

Uingiliaji / matibabu

Dietary Supplement: Korea red ginseng

Dietary Supplement: starch capsule

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Placebo Comparator: starch capsule
Dietary Supplement: starch capsule
5 capsules three times everyday for 12 weeks
Experimental: Korea red ginseng
Dietary Supplement: Korea red ginseng
5 capsules (300 mg/capsule) three times everyday for 12 weeks

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 20 Years Kwa 20 Years
Jinsia Inastahiki KujifunzaAll
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:(three or more of following five factors)

- waist circumference(male: more than 90cm, female: more than 80cm)

- blood pressure(systolic: more than 130mmHg, diastolic: more than 85mmHg)

- fasting plasma glucose: more than 100mg/dL

- fasting triglycerides: more than 150mg/dL

- High-density lipoprotein(HDL)-cholesterol(male: less than 40mg/dL, female: less than 50mg/dL)

Exclusion Criteria: (any one of following factors)

- uncontrolled blood pressure(systolic: more than 160mmHg, diastolic: more than 100mmHg) or subjects taking blood pressure lowering drug

- Type 2 diabetes patients or fasting plasma glucose more than 126mg/dL

- triglyceride more than 400mg/dL, total cholesterol more than 250mg/dL

- subjects taking antilipidemic drug

- past history of coronary heart disease or cerebrovascular disease

Matokeo

Hatua za Matokeo ya Msingi

1. Change in the Pre- and Post-treatment Systolic Blood Pressure [baseline and 12 weeks]

Hatua za Matokeo ya Sekondari

1. Change in the Pre- and Post-treatment Oxidized Low-densty Lipoprotein(LDL) [baseline and 12 weeks]

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