Laser Therapy for Perioral Dermatitis

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Kiungo kimehifadhiwa kwenye clipboard

HaliKuajiri

Wadhamini

West Virginia University

JARIBIO LA KLINIKI: NCT03779295

BioSeek: nct03779295

Maneno muhimu

Kikemikali

Perioral dermatitis is an inflammation of the skin around the mouth. The cause of perioral dermatitis is unknown. Current treatment methods include oral antibiotics and topical calcenurin inhibitors, both of which produce side effects and have been relatively ineffective in the treatment of perioral dermatitis. The investigators hope to assess the efficacy of laser therapy in treatment of perioral dermatitis by using laser therapy on one half of the patients face and having patients apply topical medication (clindamycin) to their face for 8 weeks. The side of their face that receives laser therapy will be randomized. The investigators will assess the efficacy of laser therapy by counting the number of lesions that patients have before and after laser therapy, comparing photos of patient's perioral dermatitis before and after treatment, and having patient's rate their satisfaction of the treatment.

Tarehe

Imethibitishwa Mwisho:	11/30/2018
Iliyowasilishwa Kwanza:	12/11/2018
Uandikishaji uliokadiriwa Uliwasilishwa:	12/13/2018
Iliyotumwa Kwanza:	12/18/2018
Sasisho la Mwisho Liliwasilishwa:	12/13/2018
Sasisho la Mwisho Lilichapishwa:	12/18/2018
Tarehe halisi ya kuanza kwa masomo:	10/31/2018
Tarehe ya Kukamilisha Msingi iliyokadiriwa:	02/28/2019
Tarehe ya Kukamilisha Utafiti:	03/31/2019

Hali au ugonjwa

Perioral Dermatitis

Uingiliaji / matibabu

Device: Pulse laser dye therapy (Device name: Candela Family of Pulsed Dye Laser Systems. 501k Number: K050673.)

Drug: Clindamycin

Awamu

Vikundi vya Arm

Mkono	Uingiliaji / matibabu
Experimental: Pulse laser therapy applied to right side of face
Experimental: Pulse laser therapy applied to left side of face

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza	18 Years Kwa 18 Years
Jinsia Inastahiki Kujifunza	All
Hupokea Wajitolea wa Afya	Ndio
Vigezo	Inclusion Criteria: - age 18 years or older - perioral dermatitis for greater than 1 month - willing to return for follow-up visits 2 weeks, 4 weeks and 8 weeks following treatment. Exclusion Criteria: - skin type V or VI (due to risk of hyperpigmentation) - pregnant - breastfeeding - unable to understand English - mentally impaired - incarcerated

Matokeo

Hatua za Matokeo ya Msingi

1. Change in number of lesions on side of the subject's face receiving laser therapy [initial study visit, after 4 weeks, and after 8 weeks]

counting number of lesions on each side of the face

2. Change in number of lesions on side of the subject's face receiving clindamycin alone (NO laser therapy) [initial study visit, after 4 weeks, and after 8 weeks]

counting number of lesions on each side of the face

Hatua za Matokeo ya Sekondari

1. Patient opinion of side that improved more [4 weeks, 8 weeks]

Patients will grade satisfaction of treatment by answering "Which side of their face improved more from treatment?" with the option of responding "the right side/the left side/they are the same."